Gene Expression Image Detail

Reference

Figure

ID

J:32929 Avantaggiato V, et al., Dev Biol. 1996 May 1;175(2):347-57

2

MGI:1339320

Image

Caption

Sagittal (A-O) and frontal (P-S) sections of 10.5-dpc control (A-C, P, and Q) and RA-treated embryos, respectively, at 7.4 (D-L) and 7.8 dpc (M-O, R, and S). Bright fields of corresponding sections are labeled with a prime ('). The open arrows in B,E,H,K, and N, the arrowheads in C,F,I,L, and O, and the filled arrows in D',G',K', and N' point to the position corresponding to the posterior border of Otx2 at the presumptive mid-hindbrain transition. The filled arrow in N points to the rostral-most expression of Wnt-1 in the presumptive pretectal region. Arrowheads in P,Q,R, and S point to the Otx2 and Wnt-1 expression at the midbrain/hindbrain border in control (P and Q) and 7.8-dpc RA-treated embryos (R and S); filled arrows in Q and S point to the Wnt-1 expression in the roof of the midbrain (Q) which is split into two lateral narrow stripes in 7.8-dpc RA-treated embryos (S). The large open arrow in E points to a nonspecific signal. In B' and N' the open arrows indicate the plane of sections of Q' and R', respectively. fb, forebrain; mb, midbrain; hb; hindbrain; fg, foregut.

Copyright

Reprinted with permission from Elsevier from doi:10.1006/dbio.1996.0120 Dev Biol 175: 347-57, Avantaggiato V; Acampora D; Tuorto F; Simeone A, Retinoic acid induces stage-specific repatterning of the rostral central nervous system. Copyright 1996

Associated
Assays

Label	Assay & Result Details (Gene Symbol)	Spatial Mapping
A	MGI:1339328 (Otx2)
B	MGI:1339331 (Wnt1)
C	MGI:1339330 (En2)	EMAGE:3911
B'	MGI:1339331 (Wnt1)