About   Help   FAQ
On Friday, September 29 at 7:30AM ET, access to MGI will be intermittent for a short time due to maintenance.
Vertebrate Homology
Alliance of Genome Resources

Comparative GO Graph (mouse, human, rat, zebrafish)  
Alliance Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
select all deselect all Go
human AIRE HGNC:360 (HGNC)
326 (Entrez Gene)
607358 (OMIM)
AIRE (Alliance of Genome Resources)
Chr21 q22.3 Chr21:44285838-44298648 (+)
autoimmune polyendocrine syndrome
autoimmune polyendocrine syndrome type 1
O43918 (UniProt | EBI)
NM_000659 (RefSeq)
mouse Aire MGI:1338803 (MGI)
11634 (Entrez Gene)
Gene Tree
Aire (Alliance of Genome Resources)
Chr10 39.72 cM Chr10:77865856-77879444 (-)
autoimmune polyendocrine syndrome type 1
Guillain-Barre syndrome
Sjogren's syndrome
11634 (NCBI Gene Model)
Q9Z0E3 (UniProt | EBI)
NR_073358 (RefSeq)
rat Aire RGD:1311139 (Rat Genome Database)
294328 (Entrez Gene)
Aire (Alliance of Genome Resources)
Chr20 p12 NP_001099849 (RefSeq)
NM_001106379 (RefSeq)
zebrafish aire ZDB-GENE-071008-4 (Zebrafish Model Organism Database)
100007662 (Entrez Gene)
aire (Alliance of Genome Resources)
Chr2 NP_001103484 (RefSeq)
NM_001110014 (RefSeq)
Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
MGI 6.22
The Jackson Laboratory