Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	SPRY4	HGNC:15533 (HGNC) 81848 (Entrez Gene) 607984 (OMIM) SPRY4 (Alliance of Genome Resources)	Chr5 q31.3	Chr5:142310427-142326455 (-) GRCh38	hypogonadotropic hypogonadism 17 with or without anosmia	Q9C004 (UniProt | EBI) NM_001293290 (RefSeq)
mouse	Spry4	MGI:1345144 (MGI) 24066 (Entrez Gene) Gene Tree Spry4 (Alliance of Genome Resources)	Chr18 20.5 cM	Chr18:38719300-38734400 (-) GRCm39		24066 (NCBI Gene Model) Q9WTP2 (UniProt | EBI) NM_011898 (RefSeq)
rat	Spry4	RGD:1305324 (Rat Genome Database) 291610 (Entrez Gene) Spry4 (Alliance of Genome Resources)	Chr18 p11			NP_001099620 (RefSeq) NM_001106150 (RefSeq)
zebrafish	spry4	ZDB-GENE-010803-2 (Zebrafish Model Organism Database) 114437 (Entrez Gene) spry4 (Alliance of Genome Resources)	Chr21			NP_571901 (RefSeq) NM_131826 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.