Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	AMELX	HGNC:461 (HGNC) 265 (Entrez Gene) 300391 (OMIM) AMELX (Alliance of Genome Resources)	ChrX p22.2	ChrX:11293413-11309588 (+) GRCh38	amelogenesis imperfecta amelogenesis imperfecta type 1E	Q99217 (UniProt | EBI) NM_182681 (RefSeq)
	AMELY	HGNC:462 (HGNC) 266 (Entrez Gene) 410000 (OMIM) AMELY (Alliance of Genome Resources)	ChrY p11.2	ChrY:6865918-6911752 (-) GRCh38		Q99218 (UniProt | EBI) NM_001364814 (RefSeq)
mouse	Amelx	MGI:88005 (MGI) 11704 (Entrez Gene) Gene Tree Amelx (Alliance of Genome Resources)	ChrX 78.95 cM	ChrX:167959110-167970196 (-) GRCm39	amelogenesis imperfecta type 1E	ENSMUSG00000031354 (Ensembl Gene Model) ENSMUSP00000065966 (Ensembl) ENSMUST00000066112 (Ensembl)
rat	Amelx	RGD:2107 (Rat Genome Database) 29160 (Entrez Gene) Amelx (Alliance of Genome Resources)	ChrX q13			P63278 (UniProt | EBI) NM_001271078 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.