Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	SLC12A6	HGNC:10914 (HGNC) 9990 (Entrez Gene) 604878 (OMIM) SLC12A6 (Alliance of Genome Resources)	Chr15 q14	Chr15:34229784-34338060 (-) GRCh38	agenesis of the corpus callosum with peripheral neuropathy Charcot-Marie-Tooth disease	Q9UHW9 (UniProt | EBI) NM_133647 (RefSeq)
mouse	Slc12a6	MGI:2135960 (MGI) 107723 (Entrez Gene) Gene Tree Slc12a6 (Alliance of Genome Resources)	Chr2 56.99 cM	Chr2:112096659-112193508 (+) GRCm39	agenesis of the corpus callosum with peripheral neuropathy motor peripheral neuropathy	107723 (NCBI Gene Model) Q924N4 (UniProt | EBI) NM_133649 (RefSeq)
rat	Slc12a6	RGD:1311335 (Rat Genome Database) 691209 (Entrez Gene) Slc12a6 (Alliance of Genome Resources)	Chr3 q35			NP_001103100 (RefSeq) NM_001109630 (RefSeq)
zebrafish	slc12a6	ZDB-GENE-160113-148 (Zebrafish Model Organism Database) 100330290 (Entrez Gene) slc12a6 (Alliance of Genome Resources)	Chr7			XP_009298223 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.