Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	POT1	HGNC:17284 (HGNC) 25913 (Entrez Gene) 606478 (OMIM) POT1 (Alliance of Genome Resources)	Chr7 q31.33	Chr7:124822386-124929983 (-) GRCh38	colorectal cancer familial melanoma hepatocellular carcinoma lung cancer ovarian cancer	Q9NUX5 (UniProt | EBI) NM_015450 (RefSeq)
mouse	Pot1a	MGI:2141503 (MGI) 101185 (Entrez Gene) Gene Tree Pot1a (Alliance of Genome Resources)	Chr6 11.65 cM	Chr6:25743939-25809280 (-) GRCm39		101185 (NCBI Gene Model) Q91WC1 (UniProt | EBI) NM_133931 (RefSeq)
rat	Pot1	RGD:1562696 (Rat Genome Database) 500054 (Entrez Gene) Pot1 (Alliance of Genome Resources)	Chr4 q22			NP_001382080 (RefSeq) NM_001395151 (RefSeq)
zebrafish	pot1	ZDB-GENE-110324-1 (Zebrafish Model Organism Database) 566847 (Entrez Gene) pot1 (Alliance of Genome Resources)	Chr25			NP_001232889 (RefSeq) NM_001245960 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.