Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	SLC12A5	HGNC:13818 (HGNC) 57468 (Entrez Gene) 606726 (OMIM) SLC12A5 (Alliance of Genome Resources)	Chr20 q13.12	Chr20:46021686-46060150 (+) GRCh38	developmental and epileptic encephalopathy 34 idiopathic generalized epilepsy 14	Q9H2X9 (UniProt | EBI) NM_001134771 (RefSeq)
mouse	Slc12a5	MGI:1862037 (MGI) 57138 (Entrez Gene) Gene Tree Slc12a5 (Alliance of Genome Resources)	Chr2 85.28 cM	Chr2:164802766-164841651 (+) GRCm39	epilepsy	57138 (NCBI Gene Model) Q91V14 (UniProt | EBI) NM_020333 (RefSeq)
rat	Slc12a5	RGD:620811 (Rat Genome Database) 171373 (Entrez Gene) Slc12a5 (Alliance of Genome Resources)	Chr3 q42			Q63633 (UniProt | EBI) NM_134363 (RefSeq)
zebrafish	slc12a5a	ZDB-GENE-120927-3 (Zebrafish Model Organism Database) 572215 (Entrez Gene) slc12a5a (Alliance of Genome Resources)	Chr6			XP_021332993 (RefSeq)
	slc12a5b	ZDB-GENE-080707-1 (Zebrafish Model Organism Database) 797331 (Entrez Gene) slc12a5b (Alliance of Genome Resources)	Chr8			NP_001289172 (RefSeq) NM_001302243 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.