Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	IL21R	HGNC:6006 (HGNC) 50615 (Entrez Gene) 605383 (OMIM) IL21R (Alliance of Genome Resources)	Chr16 p12.1	Chr16:27402174-27452042 (+) GRCh38	B-cell lymphoma Behcet's disease common variable immunodeficiency Crohn's disease diffuse large B-cell lymphoma human immunodeficiency virus infectious disease immunodeficiency 56 multiple sclerosis systemic lupus erythematosus temporal arteritis	Q9HBE5 (UniProt | EBI) NM_021798 (RefSeq)
mouse	Il21r	MGI:1890475 (MGI) 60504 (Entrez Gene) Gene Tree Il21r (Alliance of Genome Resources)	Chr7 68.98 cM	Chr7:125202601-125232742 (+) GRCm39		ENSMUSG00000030745 (Ensembl Gene Model) ENSMUSP00000033000 (Ensembl) ENSMUST00000033000 (Ensembl)
rat	Il21r	RGD:1304950 (Rat Genome Database) 308977 (Entrez Gene) Il21r (Alliance of Genome Resources)	Chr1 q36			NP_001012487 (RefSeq) NM_001012469 (RefSeq)
zebrafish	il21r.1	ZDB-GENE-080108-6 (Zebrafish Model Organism Database) 100134976 (Entrez Gene) il21r.1 (Alliance of Genome Resources)	Chr3			NP_001106982 (RefSeq) NM_001113510 (RefSeq)
	il21r.2	ZDB-GENE-080108-7 (Zebrafish Model Organism Database) 100134975 (Entrez Gene) il21r.2 (Alliance of Genome Resources)	Chr3			NP_001106981 (RefSeq) NM_001113509 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.