Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	PAPPA	HGNC:8602 (HGNC) 5069 (Entrez Gene) 176385 (OMIM) PAPPA (Alliance of Genome Resources)	Chr9 q33.1	Chr9:116153791-116402321 (+) GRCh38	myocardial infarction	Q13219 (UniProt | EBI) NM_002581 (RefSeq)
mouse	Pappa	MGI:97479 (MGI) 18491 (Entrez Gene) Gene Tree Pappa (Alliance of Genome Resources)	Chr4 34.14 cM	Chr4:65042411-65275746 (+) GRCm39		ENSMUSG00000028370 (Ensembl Gene Model) ENSMUSP00000081545 (Ensembl) ENSMUST00000084501 (Ensembl)
rat	Pappa	RGD:1307742 (Rat Genome Database) 313262 (Entrez Gene) Pappa (Alliance of Genome Resources)	Chr5 q24			NP_001388248 (RefSeq) NM_001401319 (RefSeq)
zebrafish	pappaa	ZDB-GENE-121113-1 (Zebrafish Model Organism Database) 101448000 (Entrez Gene) pappaa (Alliance of Genome Resources)	Chr5			NP_001265734 (RefSeq) NM_001278805 (RefSeq)
	pappab	ZDB-GENE-060526-71 (Zebrafish Model Organism Database) 101448001 (Entrez Gene) pappab (Alliance of Genome Resources)	Chr5			NP_001265737 (RefSeq) NM_001278808 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.