Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	SPG21	HGNC:20373 (HGNC) 51324 (Entrez Gene) 608181 (OMIM) SPG21 (Alliance of Genome Resources)	Chr15 q22.31	Chr15:64963022-64990310 (-) GRCh38	hereditary spastic paraplegia Mast syndrome	Q9NZD8 (UniProt | EBI) NM_001127890 (RefSeq)
mouse	Spg21	MGI:106403 (MGI) 27965 (Entrez Gene) Gene Tree Spg21 (Alliance of Genome Resources)	Chr9 35.32 cM	Chr9:65368229-65395752 (+) GRCm39	Mast syndrome	ENSMUSG00000032388 (Ensembl Gene Model) ENSMUSP00000034955 (Ensembl) ENSMUST00000034955 (Ensembl)
rat	Spg21	RGD:1359141 (Rat Genome Database) 300791 (Entrez Gene) Spg21 (Alliance of Genome Resources)	Chr8 q24			Q5XIC4 (UniProt | EBI) NM_001006987 (RefSeq)
zebrafish	spg21	ZDB-GENE-040426-2722 (Zebrafish Model Organism Database) 406704 (Entrez Gene) spg21 (Alliance of Genome Resources)	Chr7			Q6PC62 (UniProt | EBI) NM_213395 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.