Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	PDGFB	HGNC:8800 (HGNC) 5155 (Entrez Gene) 190040 (OMIM) PDGFB (Alliance of Genome Resources)	Chr22 q13.1	Chr22:39223359-39244982 (-) GRCh38	basal ganglia calcification clear cell renal cell carcinoma dermatofibrosarcoma protuberans familial meningioma glioblastoma high grade glioma prostatic hypertrophy	P01127 (UniProt | EBI) NM_002608 (RefSeq)
mouse	Pdgfb	MGI:97528 (MGI) 18591 (Entrez Gene) Gene Tree Pdgfb (Alliance of Genome Resources)	Chr15 37.85 cM	Chr15:79880075-79899178 (-) GRCm39		ENSMUSG00000000489 (Ensembl Gene Model) ENSMUSP00000000500 (Ensembl) ENSMUST00000000500 (Ensembl)
rat	Pdgfb	RGD:3283 (Rat Genome Database) 24628 (Entrez Gene) Pdgfb (Alliance of Genome Resources)	Chr7 q34			Q05028 (UniProt | EBI) NM_031524 (RefSeq)
zebrafish	pdgfba	ZDB-GENE-050208-525 (Zebrafish Model Organism Database) 798657 (Entrez Gene) pdgfba (Alliance of Genome Resources)	Chr22			NP_001410191 (RefSeq) NM_001423262 (RefSeq)
	pdgfbb	ZDB-GENE-131121-332 (Zebrafish Model Organism Database) 796490 (Entrez Gene) pdgfbb (Alliance of Genome Resources)	Chr3			XP_021329267 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.