Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	ANK2	HGNC:493 (HGNC) 287 (Entrez Gene) 106410 (OMIM) ANK2 (Alliance of Genome Resources)	Chr4 q25-q26	Chr4:112705622-113384221 (+) GRCh38	ankyrin-B-related cardiac arrhythmia atrial fibrillation long QT syndrome sick sinus syndrome	Q01484 (UniProt | EBI) NM_001354282 (RefSeq)
mouse	Ank2	MGI:88025 (MGI) 109676 (Entrez Gene) Gene Tree Ank2 (Alliance of Genome Resources)	Chr3 56.07 cM	Chr3:126715261-127292999 (-) GRCm39	ankyrin-B-related cardiac arrhythmia autistic disorder sinoatrial node disease	ENSMUSG00000032826 (Ensembl Gene Model) ENSMUSP00000138620 (Ensembl) ENSMUST00000182064 (Ensembl)
rat	Ank2	RGD:620156 (Rat Genome Database) 362036 (Entrez Gene) Ank2 (Alliance of Genome Resources)	Chr2 q42			NP_001414088 (RefSeq) NM_001427159 (RefSeq)
zebrafish	ank2a	ZDB-GENE-111215-3 (Zebrafish Model Organism Database) 568926 (Entrez Gene) ank2a (Alliance of Genome Resources)	Chr1			XP_021331700 (RefSeq)
	ank2b	ZDB-GENE-041010-165 (Zebrafish Model Organism Database) 450043 (Entrez Gene) ank2b (Alliance of Genome Resources)	Chr7			NP_001333136 (RefSeq) NM_001006063 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.