Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	NEK2	HGNC:7745 (HGNC) 4751 (Entrez Gene) 604043 (OMIM) NEK2 (Alliance of Genome Resources)	Chr1 q32.3	Chr1:211658256-211675630 (-) GRCh38	retinitis pigmentosa 67	P51955 (UniProt | EBI) NM_002497 (RefSeq)
mouse	Nek2	MGI:109359 (MGI) 18005 (Entrez Gene) Gene Tree Nek2 (Alliance of Genome Resources)	Chr1 96.94 cM	Chr1:191553556-191565162 (+) GRCm39		ENSMUSG00000026622 (Ensembl Gene Model) ENSMUSP00000027931 (Ensembl) ENSMUST00000027931 (Ensembl)
rat	Nek2	RGD:619792 (Rat Genome Database) 114482 (Entrez Gene) Nek2 (Alliance of Genome Resources)	Chr13 q27			NP_446143 (RefSeq) NM_053691 (RefSeq)
	Nek2l1	RGD:1582899 (Rat Genome Database) 690209 (Entrez Gene) Nek2l1 (Alliance of Genome Resources)	Chr8 q12
zebrafish	nek2	ZDB-GENE-040426-752 (Zebrafish Model Organism Database) 394025 (Entrez Gene) nek2 (Alliance of Genome Resources)	Chr20			NP_957344 (RefSeq) NM_201050 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.