Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	TRPV4	HGNC:18083 (HGNC) 59341 (Entrez Gene) 605427 (OMIM) TRPV4 (Alliance of Genome Resources)	Chr12 q24.11	Chr12:109783087-109833406 (-) GRCh38	autosomal dominant distal hereditary motor neuronopathy 8 Charcot-Marie-Tooth disease axonal type 2C metatropic dysplasia osteonecrosis parastremmatic dwarfism scapuloperoneal spinal muscular atrophy spondyloepiphyseal dysplasia Maroteaux type spondylometaphyseal dysplasia Kozlowski type	Q9HBA0 (UniProt | EBI) NM_147204 (RefSeq)
mouse	Trpv4	MGI:1926945 (MGI) 63873 (Entrez Gene) Gene Tree Trpv4 (Alliance of Genome Resources)	Chr5 55.99 cM	Chr5:114760213-114796482 (-) GRCm39	autosomal dominant nonsyndromic deafness 25	ENSMUSG00000014158 (Ensembl Gene Model) ENSMUSP00000107844 (Ensembl) ENSMUST00000112225 (Ensembl)
rat	Trpv4	RGD:69337 (Rat Genome Database) 66026 (Entrez Gene) Trpv4 (Alliance of Genome Resources)	Chr12 q16			Q9ERZ8 (UniProt | EBI) NM_023970 (RefSeq)
zebrafish	trpv4	ZDB-GENE-030912-7 (Zebrafish Model Organism Database) 557850 (Entrez Gene) trpv4 (Alliance of Genome Resources)	Chr5			NP_001036195 (RefSeq) NM_001042730 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.