Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	ADD1	HGNC:243 (HGNC) 118 (Entrez Gene) 102680 (OMIM) ADD1 (Alliance of Genome Resources)	Chr4 p16.3	Chr4:2843844-2930076 (+) GRCh38	atherosclerosis essential hypertension familial combined hyperlipidemia gastroschisis hypertension IgA glomerulonephritis myocardial infarction	P35611 (UniProt | EBI) NM_001354759 (RefSeq)
mouse	Add1	MGI:87918 (MGI) 11518 (Entrez Gene) Gene Tree Add1 (Alliance of Genome Resources)	Chr5 17.9 cM	Chr5:34731008-34789652 (+) GRCm39	hydrocephalus	11518 (NCBI Gene Model) Q9QYC0 (UniProt | EBI) NM_001420955 (RefSeq)
rat	Add1	RGD:2041 (Rat Genome Database) 24170 (Entrez Gene) Add1 (Alliance of Genome Resources)	Chr14 q21			Q63028 (UniProt | EBI) NM_016990 (RefSeq)
zebrafish	add1	ZDB-GENE-030909-2 (Zebrafish Model Organism Database) 555511 (Entrez Gene) add1 (Alliance of Genome Resources)	Chr21			NP_001073427 (RefSeq) NM_001079958 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.