Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	WNK1	HGNC:14540 (HGNC) 65125 (Entrez Gene) 605232 (OMIM) WNK1 (Alliance of Genome Resources)	Chr12 p13.33	Chr12:752579-911452 (+) GRCh38	hereditary sensory and autonomic neuropathy type 2A hereditary sensory neuropathy hypertension pseudohypoaldosteronism	Q9H4A3 (UniProt | EBI) NM_018979 (RefSeq)
mouse	Wnk1	MGI:2442092 (MGI) 232341 (Entrez Gene) Gene Tree Wnk1 (Alliance of Genome Resources)	Chr6 56.86 cM	Chr6:119900930-120015633 (-) GRCm39		ENSMUSG00000045962 (Ensembl Gene Model) ENSMUSP00000086017 (Ensembl) ENSMUST00000088644 (Ensembl)
rat	Wnk1	RGD:621141 (Rat Genome Database) 116477 (Entrez Gene) Wnk1 (Alliance of Genome Resources)	Chr4 q42			Q9JIH7 (UniProt | EBI) NM_001002823 (RefSeq)
zebrafish	wnk1a	ZDB-GENE-080917-49 (Zebrafish Model Organism Database) 100318736 (Entrez Gene) wnk1a (Alliance of Genome Resources)	Chr25			XP_021326361 (RefSeq)
	wnk1b	ZDB-GENE-030131-2656 (Zebrafish Model Organism Database) 561159 (Entrez Gene) wnk1b (Alliance of Genome Resources)	Chr4			XP_021330881 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.