Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	VAPB	HGNC:12649 (HGNC) 9217 (Entrez Gene) 605704 (OMIM) VAPB (Alliance of Genome Resources)	Chr20 q13.32	Chr20:58389229-58451101 (+) GRCh38	amyotrophic lateral sclerosis amyotrophic lateral sclerosis type 8 autosomal dominant adult-onset proximal spinal muscular atrophy spinal muscular atrophy	O95292 (UniProt | EBI) NM_004738 (RefSeq)
mouse	Vapb	MGI:1928744 (MGI) 56491 (Entrez Gene) Gene Tree Vapb (Alliance of Genome Resources)	Chr2 97.37 cM	Chr2:173579378-173626132 (+) GRCm39		56491 (NCBI Gene Model) Q9QY76 (UniProt | EBI) NM_019806 (RefSeq)
rat	Vapb	RGD:68326 (Rat Genome Database) 60431 (Entrez Gene) Vapb (Alliance of Genome Resources)	Chr3 q42			Q9Z269 (UniProt | EBI) NM_021847 (RefSeq)
zebrafish	vapb	ZDB-GENE-030131-2348 (Zebrafish Model Organism Database) 323628 (Entrez Gene) vapb (Alliance of Genome Resources)	Chr6			NP_997812 (RefSeq) NM_212647 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.