Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	PIK3R5	HGNC:30035 (HGNC) 23533 (Entrez Gene) 611317 (OMIM) PIK3R5 (Alliance of Genome Resources)	Chr17 p13.1	Chr17:8878911-8965712 (-) GRCh38	ataxia with oculomotor apraxia type 3 colon cancer	Q8WYR1 (UniProt | EBI) NM_001388400 (RefSeq)
mouse	Pik3r5	MGI:2443588 (MGI) 320207 (Entrez Gene) Gene Tree Pik3r5 (Alliance of Genome Resources)	Chr11 41.69 cM	Chr11:68322951-68388675 (+) GRCm39		320207 (NCBI Gene Model) Q5SW28 (UniProt | EBI) NM_177320 (RefSeq)
rat	Pik3r5	RGD:1563261 (Rat Genome Database) 497931 (Entrez Gene) Pik3r5 (Alliance of Genome Resources)	Chr10 q24			NP_001178852 (RefSeq) NM_001191923 (RefSeq)
zebrafish	pik3r5	ZDB-GENE-030131-2308 (Zebrafish Model Organism Database) 323588 (Entrez Gene) pik3r5 (Alliance of Genome Resources)	Chr6			XP_009300642 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.