Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	CAV1	HGNC:1527 (HGNC) 857 (Entrez Gene) 601047 (OMIM) CAV1 (Alliance of Genome Resources)	Chr7 q31.2	Chr7:116524994-116561185 (+) GRCh38	breast cancer breast carcinoma congenital generalized lipodystrophy type 3 diffuse scleroderma familial partial lipodystrophy limited scleroderma multiple sclerosis primary open angle glaucoma primary pulmonary hypertension prostate cancer systemic scleroderma	Q03135 (UniProt | EBI) NM_001172896 (RefSeq)
mouse	Cav1	MGI:102709 (MGI) 12389 (Entrez Gene) Gene Tree Cav1 (Alliance of Genome Resources)	Chr6 7.73 cM	Chr6:17306387-17341323 (+) GRCm39	Alzheimer's disease breast cancer hypertrophic cardiomyopathy	12389 (NCBI Gene Model) P49817 (UniProt | EBI) NM_001409565 (RefSeq)
rat	Cav1	RGD:2280 (Rat Genome Database) 25404 (Entrez Gene) Cav1 (Alliance of Genome Resources)	Chr4 q22			P41350 (UniProt | EBI) NM_031556 (RefSeq)
zebrafish	cav1	ZDB-GENE-030131-2415 (Zebrafish Model Organism Database) 323695 (Entrez Gene) cav1 (Alliance of Genome Resources)	Chr25			NP_997816 (RefSeq) NM_001024162 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.