Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	THBS1	HGNC:11785 (HGNC) 7057 (Entrez Gene) 188060 (OMIM) THBS1 (Alliance of Genome Resources)	Chr15 q14	Chr15:39581079-39599466 (+) GRCh38	cholangiocarcinoma pancreatic cancer pancreatic ductal carcinoma primary open angle glaucoma	P07996 (UniProt | EBI) NM_003246 (RefSeq)
mouse	Thbs1	MGI:98737 (MGI) 21825 (Entrez Gene) Gene Tree Thbs1 (Alliance of Genome Resources)	Chr2 59.34 cM	Chr2:117942357-117957614 (+) GRCm39	Sjogren's syndrome	21825 (NCBI Gene Model) P35441 (UniProt | EBI) NM_011580 (RefSeq)
rat	Thbs1	RGD:1588455 (Rat Genome Database) 445442 (Entrez Gene) Thbs1 (Alliance of Genome Resources)	Chr3			NP_001013080 (RefSeq) NM_001398940 (RefSeq)
zebrafish	thbs1a	ZDB-GENE-120402-2 (Zebrafish Model Organism Database) 100332237 (Entrez Gene) thbs1a (Alliance of Genome Resources)	ChrUN			XP_002667003 (RefSeq)
	thbs1b	ZDB-GENE-020708-1 (Zebrafish Model Organism Database) 561901 (Entrez Gene) thbs1b (Alliance of Genome Resources)	Chr20			XP_690395 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.