Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ZP2
  • Mouse genes Zp2
  • Rat genes Zp2
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Zp2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0032190	acrosin binding	ZP2	IPI	UniProtKB:P10323	Human	PMID:15950651
Molecular Function	GO:0042802	identical protein binding	ZP2	IPI	UniProtKB:Q05996	Human	PMID:26879157
Molecular Function	GO:0005515	protein binding	ZP2	IPI	UniProtKB:P10323	Human	PMID:15950651
Molecular Function	GO:0005515	protein binding	ZP2	IPI	UniProtKB:P04406	Human	PMID:23355646
Molecular Function	GO:0005515	protein binding	ZP2	IPI	UniProtKB:P06733	Human	PMID:23355646
Molecular Function	GO:0005515	protein binding	ZP2	IPI	UniProtKB:P14618-3	Human	PMID:23355646
Molecular Function	GO:0005515	protein binding	ZP2	IPI	UniProtKB:P36969	Human	PMID:23355646
Molecular Function	GO:0005515	protein binding	ZP2	IPI	UniProtKB:P45880	Human	PMID:23355646
Molecular Function	GO:0005515	protein binding	ZP2	IPI	UniProtKB:P45880-3	Human	PMID:23355646
Molecular Function	GO:0005515	protein binding	ZP2	IPI	UniProtKB:P21754	Human	PMID:28886344
Molecular Function	GO:0005515	protein binding	Zp2	IPI	PR:P23578	Mouse	PMID:11739644
Molecular Function	GO:0035804	structural constituent of egg coat	ZP2	IMP		Human	PMID:29895852
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Zp2	IDA		Mouse	MGI:MGI:2177349|PMID:11906903
Cellular Component	GO:0035805	egg coat	ZP2	IDA		Human	PMID:29895852
Cellular Component	GO:0005783	endoplasmic reticulum	Zp2	IDA		Mouse	MGI:MGI:3690518|PMID:17047254
Cellular Component	GO:0005771	multivesicular body	Zp2	IDA		Mouse	MGI:MGI:3690518|PMID:17047254
Cellular Component	GO:0005886	plasma membrane	Zp2	IDA		Mouse	MGI:MGI:3690518|PMID:17047254
Biological Process	GO:0007339	binding of sperm to zona pellucida	Zp2	IDA		Mouse	MGI:MGI:5427546|PMID:22472438
Biological Process	GO:0007339	binding of sperm to zona pellucida	Zp2	IDA		Mouse	PMID:11739644
Biological Process	GO:0060468	prevention of polyspermy	Zp2	IDA		Mouse	MGI:MGI:5427546|PMID:22472438

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern