Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ZFYVE1
  • Mouse genes Zfyve1
  • Rat genes Zfyve1
  • Zfish genes zfyve1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Zfyve1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005545	1-phosphatidylinositol binding	ZFYVE1	IDA		Human	PMID:11256955
Molecular Function	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	ZFYVE1	IDA		Human	PMID:11804589
Molecular Function	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	ZFYVE1	IDA		Human	PMID:11804589
Molecular Function	GO:0032266	phosphatidylinositol-3-phosphate binding	ZFYVE1	IDA		Human	PMID:31293035
Molecular Function	GO:0005515	protein binding	ZFYVE1	IPI	UniProtKB:P62136	Human	PMID:19389623
Molecular Function	GO:0005515	protein binding	ZFYVE1	IPI	UniProtKB:O43264	Human	PMID:30970241
Molecular Function	GO:0005515	protein binding	ZFYVE1	IPI	UniProtKB:Q96G97	Human	PMID:30970241
Molecular Function	GO:0005515	protein binding	ZFYVE1	IPI	UniProtKB:Q9NP72	Human	PMID:30970241
Molecular Function	GO:0005515	protein binding	ZFYVE1	IPI	UniProtKB:Q9NP72	Human	PMID:31293035
Molecular Function	GO:0005515	protein binding	ZFYVE1	IPI	UniProtKB:Q96A72	Human	PMID:32296183
Cellular Component	GO:0005776	autophagosome	ZFYVE1	IDA		Human	PMID:22456507
Cellular Component	GO:0005783	endoplasmic reticulum	ZFYVE1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005783	endoplasmic reticulum	ZFYVE1	IDA		Human	PMID:11739631
Cellular Component	GO:0005783	endoplasmic reticulum	ZFYVE1	IDA		Human	PMID:25876663
Cellular Component	GO:0005783	endoplasmic reticulum	Zfyve1	IDA		Mouse	MGI:MGI:6393342|PMID:25876663
Cellular Component	GO:0005789	endoplasmic reticulum membrane	ZFYVE1	IDA		Human	PMID:30970241
Cellular Component	GO:0097629	extrinsic component of omegasome membrane	ZFYVE1	IDA		Human	PMID:19898463
Cellular Component	GO:0005794	Golgi apparatus	ZFYVE1	IDA		Human	PMID:25876663
Cellular Component	GO:0005794	Golgi apparatus	Zfyve1	IDA		Mouse	MGI:MGI:6393342|PMID:25876663
Cellular Component	GO:0005795	Golgi stack	ZFYVE1	IDA		Human	PMID:11256955
Cellular Component	GO:0005811	lipid droplet	ZFYVE1	IDA		Human	PMID:30970241
Cellular Component	GO:0005811	lipid droplet	ZFYVE1	IDA		Human	PMID:31293035
Cellular Component	GO:0005811	lipid droplet	Zfyve1	IDA		Mouse	MGI:MGI:6393373|PMID:31293035
Cellular Component	GO:0016020	membrane	ZFYVE1	IDA		Human	PMID:25578879
Cellular Component	GO:0044233	mitochondria-associated endoplasmic reticulum membrane	ZFYVE1	IDA		Human	PMID:23455425
Cellular Component	GO:0005739	mitochondrion	ZFYVE1	IDA		Human	PMID:25876663
Cellular Component	GO:0005739	mitochondrion	Zfyve1	IDA		Mouse	MGI:MGI:6393342|PMID:25876663
Cellular Component	GO:1990462	omegasome	ZFYVE1	IDA		Human	PMID:24954904
Cellular Component	GO:1990462	omegasome	ZFYVE1	IDA		Human	PMID:25876663
Cellular Component	GO:1990462	omegasome	ZFYVE1	IDA		Human	PMID:31293035
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ZFYVE1	IDA		Human	PMID:11739631
Cellular Component	GO:0000407	phagophore assembly site	ZFYVE1	IDA		Human	PMID:23455425
Cellular Component	GO:0000407	phagophore assembly site	ZFYVE1	IDA		Human	PMID:33499712
Biological Process	GO:0009267	cellular response to starvation	ZFYVE1	IDA		Human	PMID:25578879
Biological Process	GO:0140042	lipid droplet formation	ZFYVE1	IMP		Human	PMID:30970241
Biological Process	GO:0140042	lipid droplet formation	Zfyve1	IMP		Mouse	MGI:MGI:6392989|PMID:30970241
Biological Process	GO:0016236	macroautophagy	ZFYVE1	IDA		Human	PMID:25578879

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern