Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ZNF703
  • Mouse genes Zfp703
  • Rat genes Zfp703
  • Zfish genes znf703
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Zfp703

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0140297	DNA-binding transcription factor binding	Zfp703	IPI	UniProtKB:Q62441	Mouse	MGI:MGI:4940410|PMID:21317240
Molecular Function	GO:0042826	histone deacetylase binding	znf703	IDA		Zfish	PMID:14709556
Molecular Function	GO:0042802	identical protein binding	znf703	IPI	UniProtKB:Q90YM7	Zfish	PMID:14709556
Molecular Function	GO:0005515	protein binding	ZNF703	IPI	UniProtKB:P61962	Human	PMID:21328542
Molecular Function	GO:0005515	protein binding	ZNF703	IPI	UniProtKB:Q99623	Human	PMID:21328542
Molecular Function	GO:0005515	protein binding	znf703	IPI	UniProtKB:Q98TH2	Zfish	PMID:14550789
Molecular Function	GO:0005515	protein binding	znf703	IPI	UniProtKB:Q803U2	Zfish	PMID:14709556
Cellular Component	GO:0005737	cytoplasm	ZNF703	IDA		Human	PMID:21328542
Cellular Component	GO:0005737	cytoplasm	Zfp703	IDA		Mouse	MGI:MGI:4940410|PMID:21317240
Cellular Component	GO:0000118	histone deacetylase complex	znf703	IDA		Zfish	PMID:14709556
Cellular Component	GO:0016363	nuclear matrix	ZNF703	IDA		Human	PMID:21328542
Cellular Component	GO:0005634	nucleus	ZNF703	IDA		Human	PMID:21328542
Cellular Component	GO:0005634	nucleus	ZNF703	IDA		Human	PMID:21337521
Cellular Component	GO:0005634	nucleus	Zfp703	IDA		Mouse	MGI:MGI:4940410|PMID:21317240
Cellular Component	GO:0005634	nucleus	znf703	IDA		Zfish	PMID:14709556
Cellular Component	GO:0005634	nucleus	znf703	IDA		Zfish	PMID:14550789
Cellular Component	GO:0032991	protein-containing complex	ZNF703	IDA		Human	PMID:21328542
Biological Process	GO:0034333	adherens junction assembly	Zfp703	IDA		Mouse	MGI:MGI:4940410|PMID:21317240
Biological Process	GO:0007420	brain development	znf703	IMP		Zfish	PMID:14550789
Biological Process	GO:0007420	brain development	znf703	IEP		Zfish	PMID:14550789
Biological Process	GO:0071392	cellular response to estradiol stimulus	ZNF703	IDA		Human	PMID:21328542
Biological Process	GO:0060271	cilium assembly	znf703	IMP	ZFIN:ZDB-MRPHLNO-090413-3	Zfish	PMID:26327644
Biological Process	GO:0060271	cilium assembly	znf703	IMP	ZFIN:ZDB-CRISPR-160202-1	Zfish	PMID:26327644
Biological Process	GO:0007368	determination of left/right symmetry	znf703	IMP	ZFIN:ZDB-CRISPR-160202-1	Zfish	PMID:26327644
Biological Process	GO:0007368	determination of left/right symmetry	znf703	IMP	ZFIN:ZDB-MRPHLNO-090413-3	Zfish	PMID:26327644
Biological Process	GO:0048596	embryonic camera-type eye morphogenesis	znf703	IMP	ZFIN:ZDB-MRPHLNO-090413-3	Zfish	PMID:19171890
Biological Process	GO:0048596	embryonic camera-type eye morphogenesis	znf703	IGI	ZFIN:ZDB-GENE-990415-8,ZFIN:ZDB-MRPHLNO-090413-3	Zfish	PMID:19171890
Biological Process	GO:0030902	hindbrain development	znf703	IGI	ZFIN:ZDB-GENE-031113-5	Zfish	PMID:15042707
Biological Process	GO:0060644	mammary gland epithelial cell differentiation	ZNF703	IDA		Human	PMID:21337521
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ZNF703	IMP		Human	PMID:21337521
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Zfp703	IDA		Mouse	MGI:MGI:4940410|PMID:21317240
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	znf703	IPI	UniProtKB:Q98TH2	Zfish	PMID:14550789
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	znf703	IMP		Zfish	PMID:14550789
Biological Process	GO:0034111	negative regulation of homotypic cell-cell adhesion	Zfp703	IDA		Mouse	MGI:MGI:4940410|PMID:21317240
Biological Process	GO:0030335	positive regulation of cell migration	Zfp703	IDA		Mouse	MGI:MGI:4940410|PMID:21317240
Biological Process	GO:0008284	positive regulation of cell population proliferation	ZNF703	IDA		Human	PMID:21328542
Biological Process	GO:0010718	positive regulation of epithelial to mesenchymal transition	Zfp703	IDA		Mouse	MGI:MGI:4940410|PMID:21317240
Biological Process	GO:0031065	positive regulation of histone deacetylation	znf703	IDA		Zfish	PMID:19014486
Biological Process	GO:0033601	positive regulation of mammary gland epithelial cell proliferation	ZNF703	IDA		Human	PMID:21337521
Biological Process	GO:0033601	positive regulation of mammary gland epithelial cell proliferation	Zfp703	IDA		Mouse	MGI:MGI:4940410|PMID:21317240
Biological Process	GO:0060828	regulation of canonical Wnt signaling pathway	Zfp703	IDA		Mouse	MGI:MGI:4940410|PMID:21317240
Biological Process	GO:0051726	regulation of cell cycle	ZNF703	IDA		Human	PMID:21328542
Biological Process	GO:0006355	regulation of DNA-templated transcription	ZNF703	IDA		Human	PMID:21328542
Biological Process	GO:0017015	regulation of transforming growth factor beta receptor signaling pathway	ZNF703	IDA		Human	PMID:21337521
Biological Process	GO:0017015	regulation of transforming growth factor beta receptor signaling pathway	Zfp703	IDA		Mouse	MGI:MGI:4940410|PMID:21317240

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern