Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ZFP57
  • Mouse genes Zfp57
  • Rat genes Zfp57
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Zfp57

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	ZFP57	IDA		Human	PMID:30602440
Molecular Function	GO:0003682	chromatin binding	Zfp57	IDA		Mouse	MGI:MGI:6284037|PMID:30602440
Molecular Function	GO:0003677	DNA binding	Zfp57	IDA		Mouse	PMID:22495301
Molecular Function	GO:0010385	double-stranded methylated DNA binding	Zfp57	IDA		Mouse	MGI:MGI:6284037|PMID:30602440
Molecular Function	GO:0005515	protein binding	Zfp57	IPI	UniProtKB:Q13263	Mouse	MGI:MGI:3826319|PMID:18854139
Cellular Component	GO:0000792	heterochromatin	Zfp57	IDA		Mouse	PMID:15070898
Cellular Component	GO:0005634	nucleus	Zfp57	IDA		Mouse	MGI:MGI:6284037|PMID:30602440
Cellular Component	GO:0005634	nucleus	Zfp57	IDA		Mouse	PMID:8120052
Cellular Component	GO:0005634	nucleus	Zfp57	IDA		Mouse	PMID:15070898
Biological Process	GO:0043045	DNA methylation involved in embryo development	ZFP57	IMP		Human	PMID:18622393
Biological Process	GO:0043045	DNA methylation involved in embryo development	Zfp57	IMP		Mouse	MGI:MGI:3826319|PMID:18854139
Biological Process	GO:0043045	DNA methylation involved in embryo development	Zfp57	IMP	MGI:MGI:3826984	Mouse	PMID:33500348
Biological Process	GO:0071514	genomic imprinting	Zfp57	IMP	MGI:MGI:3826984	Mouse	PMID:33500348
Biological Process	GO:0044027	negative regulation of gene expression via CpG island methylation	Zfp57	IGI	UniProtKB:Q8R2V3	Mouse	MGI:MGI:6284037|PMID:30602440
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Zfp57	IDA		Mouse	PMID:15070898
Biological Process	GO:0006349	regulation of gene expression by genomic imprinting	ZFP57	IMP		Human	PMID:18622393
Biological Process	GO:0006349	regulation of gene expression by genomic imprinting	Zfp57	IMP		Mouse	MGI:MGI:3826319|PMID:18854139
Biological Process	GO:0006349	regulation of gene expression by genomic imprinting	Zfp57	IMP	MGI:MGI:3826984	Mouse	PMID:33500348
Biological Process	GO:2000653	regulation of genetic imprinting	Zfp57	IGI	UniProtKB:Q8R2V3	Mouse	MGI:MGI:6284037|PMID:30602440

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern