Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ZNF516
  • Mouse genes Zfp516
  • Rat genes Zfp516
  • Zfish genes znf516
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Zfp516

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0000987	cis-regulatory region sequence-specific DNA binding	Zfp516	IDA		Mouse	MGI:MGI:5616937|PMID:25578880
Molecular Function	GO:0140297	DNA-binding transcription factor binding	Zfp516	IPI	UniProtKB:Q9HAZ2	Mouse	MGI:MGI:5616937|PMID:25578880
Molecular Function	GO:0005515	protein binding	ZNF516	IPI	UniProtKB:Q13547	Human	PMID:23752268
Molecular Function	GO:0005515	protein binding	ZNF516	IPI	UniProtKB:Q13363	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	ZNF516	IPI	UniProtKB:Q13547	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	ZNF516	IPI	UniProtKB:O60341	Human	PMID:28947780
Molecular Function	GO:0005515	protein binding	ZNF516	IPI	UniProtKB:P56545	Human	PMID:28947780
Molecular Function	GO:0005515	protein binding	ZNF516	IPI	UniProtKB:Q13363	Human	PMID:28947780
Molecular Function	GO:0005515	protein binding	ZNF516	IPI	UniProtKB:Q13547	Human	PMID:28947780
Molecular Function	GO:0005515	protein binding	ZNF516	IPI	UniProtKB:Q92769	Human	PMID:28947780
Molecular Function	GO:0005515	protein binding	ZNF516	IPI	UniProtKB:Q9UKL0	Human	PMID:28947780
Molecular Function	GO:0005515	protein binding	ZNF516	IPI	UniProtKB:Q13363	Human	PMID:31041561
Molecular Function	GO:0005515	protein binding	ZNF516	IPI	UniProtKB:Q13363	Human	PMID:35016035
Molecular Function	GO:0005515	protein binding	Zfp516	IPI	UniProtKB:E9Q9M8|UniProtKB:O09106	Mouse	MGI:MGI:6867105|PMID:34180153
Cellular Component	GO:0005634	nucleus	Zfp516	IDA		Mouse	MGI:MGI:5616937|PMID:25578880
Biological Process	GO:0060612	adipose tissue development	Zfp516	IMP		Mouse	MGI:MGI:5616937|PMID:25578880
Biological Process	GO:0050873	brown fat cell differentiation	Zfp516	IMP		Mouse	MGI:MGI:5616937|PMID:25578880
Biological Process	GO:0120162	positive regulation of cold-induced thermogenesis	Zfp516	IMP		Mouse	MGI:MGI:5616937|PMID:25578880
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Zfp516	IDA		Mouse	MGI:MGI:5616937|PMID:25578880
Biological Process	GO:0009409	response to cold	Zfp516	IDA		Mouse	MGI:MGI:5616937|PMID:25578880

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern