Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ZCCHC3
  • Mouse genes Zcchc3
  • Rat genes Zcchc3
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Zcchc3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003690	double-stranded DNA binding	ZCCHC3	IDA		Human	PMID:30135424
Molecular Function	GO:0005515	protein binding	ZCCHC3	IPI	UniProtKB:Q8N884	Human	PMID:30135424
Molecular Function	GO:0005515	protein binding	ZCCHC3	IPI	UniProtKB:O95786	Human	PMID:30193849
Molecular Function	GO:0005515	protein binding	ZCCHC3	IPI	UniProtKB:Q9BYX4	Human	PMID:30193849
Molecular Function	GO:0003723	RNA binding	ZCCHC3	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	ZCCHC3	HDA		Human	PMID:22681889
Cellular Component	GO:0005737	cytoplasm	ZCCHC3	IDA		Human	PMID:30135424
Biological Process	GO:0002218	activation of innate immune response	ZCCHC3	IDA		Human	PMID:30135424
Biological Process	GO:0002218	activation of innate immune response	ZCCHC3	IDA		Human	PMID:30193849
Biological Process	GO:0002218	activation of innate immune response	Zcchc3	IMP		Mouse	MGI:MGI:6209107|PMID:30135424
Biological Process	GO:0002218	activation of innate immune response	Zcchc3	IMP		Mouse	MGI:MGI:6271678|PMID:30193849
Biological Process	GO:0071360	cellular response to exogenous dsRNA	ZCCHC3	IMP		Human	PMID:30193849
Biological Process	GO:0071360	cellular response to exogenous dsRNA	Zcchc3	IMP		Mouse	MGI:MGI:6271678|PMID:30193849
Biological Process	GO:0051607	defense response to virus	Zcchc3	IMP		Mouse	MGI:MGI:6209107|PMID:30135424
Biological Process	GO:0051607	defense response to virus	Zcchc3	IMP		Mouse	MGI:MGI:6271678|PMID:30193849
Biological Process	GO:0009597	detection of virus	ZCCHC3	IDA		Human	PMID:30135424
Biological Process	GO:0009597	detection of virus	ZCCHC3	IDA		Human	PMID:30193849
Biological Process	GO:1900246	positive regulation of RIG-I signaling pathway	ZCCHC3	IDA		Human	PMID:30193849
Biological Process	GO:0032481	positive regulation of type I interferon production	Zcchc3	IMP		Mouse	MGI:MGI:6209107|PMID:30135424

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern