Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Ythdf2

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes YTHDF2
- Mouse genes Ythdf2
- Rat genes Ythdf2
- Zfish genes ythdf2
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ythdf2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0062153	C5-methylcytidine-containing RNA binding	YTHDF2	IDA		Human	PMID:31815440
Molecular Function	GO:1990247	N6-methyladenosine-containing RNA binding	YTHDF2	IDA		Human	PMID:22575960
Molecular Function	GO:1990247	N6-methyladenosine-containing RNA binding	YTHDF2	IDA		Human	PMID:24284625
Molecular Function	GO:1990247	N6-methyladenosine-containing RNA binding	YTHDF2	IDA		Human	PMID:25412658
Molecular Function	GO:1990247	N6-methyladenosine-containing RNA binding	YTHDF2	IDA		Human	PMID:25412661
Molecular Function	GO:1990247	N6-methyladenosine-containing RNA binding	YTHDF2	IDA		Human	PMID:26046440
Molecular Function	GO:1990247	N6-methyladenosine-containing RNA binding	YTHDF2	IDA		Human	PMID:26318451
Molecular Function	GO:1990247	N6-methyladenosine-containing RNA binding	YTHDF2	IDA		Human	PMID:26458103
Molecular Function	GO:1990247	N6-methyladenosine-containing RNA binding	YTHDF2	IDA		Human	PMID:27558897
Molecular Function	GO:1990247	N6-methyladenosine-containing RNA binding	YTHDF2	IDA		Human	PMID:28106072
Molecular Function	GO:1990247	N6-methyladenosine-containing RNA binding	YTHDF2	IDA		Human	PMID:30559377
Molecular Function	GO:1990247	N6-methyladenosine-containing RNA binding	YTHDF2	IDA		Human	PMID:30930054
Molecular Function	GO:1990247	N6-methyladenosine-containing RNA binding	YTHDF2	IDA		Human	PMID:31292544
Molecular Function	GO:1990247	N6-methyladenosine-containing RNA binding	YTHDF2	IDA		Human	PMID:32169943
Molecular Function	GO:1990247	N6-methyladenosine-containing RNA binding	YTHDF2	IDA		Human	PMID:32451507
Molecular Function	GO:1990247	N6-methyladenosine-containing RNA binding	YTHDF2	IDA		Human	PMID:32492408
Molecular Function	GO:1990247	N6-methyladenosine-containing RNA binding	Ythdf2	IMP		Mouse	MGI:MGI:6316439\|PMID:29855337
Molecular Function	GO:1990247	N6-methyladenosine-containing RNA binding	ythdf2	IDA		Zfish	PMID:28192787\|ZFIN:ZDB-PUB-170214-2
Molecular Function	GO:1990247	N6-methyladenosine-containing RNA binding	ythdf2	IDA		Zfish	PMID:28869969\|ZFIN:ZDB-PUB-170905-1
Molecular Function	GO:0005515	protein binding	YTHDF2	IPI	UniProtKB:P19712:PRO_0000038050	Human	PMID:24965446
Molecular Function	GO:0005515	protein binding	YTHDF2	IPI	UniProtKB:Q7Z739	Human	PMID:28106072
Molecular Function	GO:0005515	protein binding	YTHDF2	IPI	UniProtKB:P52758	Human	PMID:30930054
Molecular Function	GO:0003723	RNA binding	YTHDF2	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	YTHDF2	HDA		Human	PMID:22681889
Cellular Component	GO:0034451	centriolar satellite	YTHDF2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005737	cytoplasm	YTHDF2	IDA		Human	PMID:32492408
Cellular Component	GO:0005737	cytoplasm	Ythdf2	IDA		Mouse	MGI:MGI:5911735\|PMID:28867294
Cellular Component	GO:0005737	cytoplasm	Ythdf2	IDA		Mouse	MGI:MGI:6490006\|PMID:32943573
Cellular Component	GO:0036464	cytoplasmic ribonucleoprotein granule	YTHDF2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0010494	cytoplasmic stress granule	YTHDF2	IDA		Human	PMID:31292544
Cellular Component	GO:0010494	cytoplasmic stress granule	YTHDF2	IDA		Human	PMID:32451507
Cellular Component	GO:0005829	cytosol	YTHDF2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	YTHDF2	IDA		Human	PMID:26458103
Cellular Component	GO:0005634	nucleus	YTHDF2	IDA		Human	PMID:26458103
Cellular Component	GO:0005634	nucleus	Ythdf2	IMP		Mouse	MGI:MGI:6490006\|PMID:32943573
Cellular Component	GO:0000932	P-body	YTHDF2	IDA		Human	PMID:24284625
Cellular Component	GO:0000932	P-body	YTHDF2	IDA		Human	PMID:31292544
Cellular Component	GO:0000932	P-body	YTHDF2	IDA		Human	PMID:32492408
Biological Process	GO:0048598	embryonic morphogenesis	ythdf2	IMP		Zfish	PMID:28192787\|ZFIN:ZDB-PUB-170214-2
Biological Process	GO:0098508	endothelial to hematopoietic transition	ythdf2	IMP		Zfish	PMID:28869969\|ZFIN:ZDB-PUB-170905-1
Biological Process	GO:0007276	gamete generation	Ythdf2	IMP		Mouse	MGI:MGI:6490006\|PMID:32943573
Biological Process	GO:0071425	hematopoietic stem cell proliferation	Ythdf2	IMP		Mouse	MGI:MGI:6317061\|PMID:30150673
Biological Process	GO:0071425	hematopoietic stem cell proliferation	Ythdf2	IMP		Mouse	MGI:MGI:6316688\|PMID:30065315
Biological Process	GO:0071425	hematopoietic stem cell proliferation	ythdf2	IMP	ZFIN:ZDB-MRPHLNO-170406-5	Zfish	PMID:28869969
Biological Process	GO:0006402	mRNA catabolic process	YTHDF2	IDA		Human	PMID:27558897
Biological Process	GO:0006402	mRNA catabolic process	YTHDF2	IDA		Human	PMID:30559377
Biological Process	GO:0006402	mRNA catabolic process	YTHDF2	IDA		Human	PMID:30930054
Biological Process	GO:0006402	mRNA catabolic process	Ythdf2	IMP		Mouse	MGI:MGI:6316439\|PMID:29855337
Biological Process	GO:0006402	mRNA catabolic process	Ythdf2	IMP		Mouse	MGI:MGI:6317061\|PMID:30150673
Biological Process	GO:0006402	mRNA catabolic process	Ythdf2	IMP		Mouse	MGI:MGI:6316688\|PMID:30065315
Biological Process	GO:0006402	mRNA catabolic process	ythdf2	IMP	ZFIN:ZDB-GENO-170505-3	Zfish	PMID:28192787
Biological Process	GO:0061157	mRNA destabilization	YTHDF2	IDA		Human	PMID:27558897
Biological Process	GO:0061157	mRNA destabilization	YTHDF2	IMP		Human	PMID:28106072
Biological Process	GO:0061157	mRNA destabilization	YTHDF2	IDA		Human	PMID:30559377
Biological Process	GO:0061157	mRNA destabilization	YTHDF2	IDA		Human	PMID:30930054
Biological Process	GO:0061157	mRNA destabilization	YTHDF2	IMP		Human	PMID:32169943
Biological Process	GO:0061157	mRNA destabilization	YTHDF2	IDA		Human	PMID:32492408
Biological Process	GO:0061157	mRNA destabilization	Ythdf2	IMP		Mouse	MGI:MGI:6490006\|PMID:32943573
Biological Process	GO:0061157	mRNA destabilization	Ythdf2	IMP		Mouse	MGI:MGI:6316439\|PMID:29855337
Biological Process	GO:0061157	mRNA destabilization	Ythdf2	IMP		Mouse	MGI:MGI:6508516\|PMID:31959747
Biological Process	GO:0061157	mRNA destabilization	Ythdf2	IMP		Mouse	MGI:MGI:6316688\|PMID:30065315
Biological Process	GO:0061157	mRNA destabilization	Ythdf2	IMP		Mouse	MGI:MGI:6317061\|PMID:30150673
Biological Process	GO:0061157	mRNA destabilization	ythdf2	IDA		Zfish	PMID:28192787\|ZFIN:ZDB-PUB-170214-2
Biological Process	GO:0045746	negative regulation of Notch signaling pathway	ythdf2	IMP		Zfish	PMID:28869969\|ZFIN:ZDB-PUB-170905-1
Biological Process	GO:0045746	negative regulation of Notch signaling pathway	ythdf2	IMP	ZFIN:ZDB-MRPHLNO-170406-5	Zfish	PMID:28869969
Biological Process	GO:2000737	negative regulation of stem cell differentiation	YTHDF2	IMP		Human	PMID:32169943
Biological Process	GO:0060339	negative regulation of type I interferon-mediated signaling pathway	YTHDF2	IMP		Human	PMID:30559377
Biological Process	GO:0001556	oocyte maturation	Ythdf2	IMP		Mouse	MGI:MGI:5911735\|PMID:28867294
Biological Process	GO:0070925	organelle assembly	YTHDF2	IDA		Human	PMID:31292544
Biological Process	GO:1903679	positive regulation of cap-independent translational initiation	YTHDF2	IDA		Human	PMID:26458103
Biological Process	GO:0030155	regulation of cell adhesion	Ythdf2	IMP		Mouse	MGI:MGI:6508516\|PMID:31959747
Biological Process	GO:1902036	regulation of hematopoietic stem cell differentiation	Ythdf2	IMP		Mouse	MGI:MGI:6316688\|PMID:30065315
Biological Process	GO:1902036	regulation of hematopoietic stem cell differentiation	Ythdf2	IMP		Mouse	MGI:MGI:6317061\|PMID:30150673
Biological Process	GO:1902036	regulation of hematopoietic stem cell differentiation	ythdf2	IMP		Zfish	PMID:28869969\|ZFIN:ZDB-PUB-170905-1
Biological Process	GO:1903538	regulation of meiotic cell cycle process involved in oocyte maturation	Ythdf2	IMP		Mouse	MGI:MGI:5911735\|PMID:28867294
Biological Process	GO:0043488	regulation of mRNA stability	YTHDF2	IMP		Human	PMID:24284625
Biological Process	GO:0043488	regulation of mRNA stability	YTHDF2	IMP		Human	PMID:26046440
Biological Process	GO:0043488	regulation of mRNA stability	YTHDF2	IDA		Human	PMID:32492408
Biological Process	GO:0043488	regulation of mRNA stability	Ythdf2	IMP		Mouse	MGI:MGI:6490006\|PMID:32943573
Biological Process	GO:0050767	regulation of neurogenesis	YTHDF2	IMP		Human	PMID:32169943
Biological Process	GO:0050767	regulation of neurogenesis	Ythdf2	IMP		Mouse	MGI:MGI:6316439\|PMID:29855337
Biological Process	GO:2000232	regulation of rRNA processing	YTHDF2	IMP		Human	PMID:31815440
Biological Process	GO:0006401	RNA catabolic process	ythdf2	IMP	ZFIN:ZDB-GENO-170505-3	Zfish	PMID:28192787
Biological Process	GO:0007284	spermatogonial cell division	Ythdf2	IMP		Mouse	MGI:MGI:6508516\|PMID:31959747
Biological Process	GO:0034063	stress granule assembly	YTHDF2	IDA		Human	PMID:32451507

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 05/14/2024 MGI 6.23

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.