Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes YARS2
  • Mouse genes Yars2
  • Rat genes Yars2
  • Zfish genes yars2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Yars2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	YARS2	IPI	UniProtKB:Q8IZU0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	YARS2	IPI	UniProtKB:Q6RW13-2	Human	PMID:32296183
Molecular Function	GO:0042803	protein homodimerization activity	YARS2	IPI	UniProtKB:Q6PI48	Human	PMID:15779907
Molecular Function	GO:0042803	protein homodimerization activity	YARS2	IPI	UniProtKB:Q9Y2Z4	Human	PMID:17997975
Molecular Function	GO:0003723	RNA binding	YARS2	HDA		Human	PMID:22681889
Molecular Function	GO:0000049	tRNA binding	YARS2	IDA		Human	PMID:20598274
Molecular Function	GO:0072545	tyrosine binding	YARS2	IDA		Human	PMID:17997975
Molecular Function	GO:0004831	tyrosine-tRNA ligase activity	YARS2	IDA		Human	PMID:15779907
Molecular Function	GO:0004831	tyrosine-tRNA ligase activity	YARS2	IDA		Human	PMID:15840810
Molecular Function	GO:0004831	tyrosine-tRNA ligase activity	YARS2	IDA		Human	PMID:17997975
Molecular Function	GO:0004831	tyrosine-tRNA ligase activity	YARS2	IDA		Human	PMID:20598274
Cellular Component	GO:0005739	mitochondrion	YARS2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005739	mitochondrion	Yars2	HDA		Mouse	PMID:18614015
Cellular Component	GO:0016604	nuclear body	YARS2	IDA		Human	GO_REF:0000052
Biological Process	GO:0070184	mitochondrial tyrosyl-tRNA aminoacylation	YARS2	IMP		Human	PMID:20598274
Biological Process	GO:0043039	tRNA aminoacylation	YARS2	IDA		Human	PMID:15779907
Biological Process	GO:0043039	tRNA aminoacylation	YARS2	IDA		Human	PMID:15840810
Biological Process	GO:0043039	tRNA aminoacylation	YARS2	IDA		Human	PMID:17997975

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern