Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes WDR77
  • Mouse genes Wdr77
  • Rat genes Wdr77
  • Zfish genes wdr77
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Wdr77

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008327	methyl-CpG binding	WDR77	IDA		Human	PMID:25284789
Molecular Function	GO:0030374	nuclear receptor coactivator activity	WDR77	IGI	UniProtKB:P10275	Human	PMID:12972618
Molecular Function	GO:0005515	protein binding	WDR77	IPI	UniProtKB:O14744	Human	PMID:11756452
Molecular Function	GO:0005515	protein binding	WDR77	IPI	UniProtKB:Q8BUV6	Human	PMID:16087681
Molecular Function	GO:0005515	protein binding	WDR77	IPI	UniProtKB:P27695	Human	PMID:19188445
Molecular Function	GO:0005515	protein binding	WDR77	IPI	UniProtKB:O14744	Human	PMID:20951943
Molecular Function	GO:0005515	protein binding	WDR77	IPI	UniProtKB:O14744	Human	PMID:22365833
Molecular Function	GO:0005515	protein binding	WDR77	IPI	UniProtKB:O14744	Human	PMID:23071334
Molecular Function	GO:0005515	protein binding	WDR77	IPI	UniProtKB:O14744	Human	PMID:23892143
Molecular Function	GO:0005515	protein binding	WDR77	IPI	UniProtKB:P03418	Human	PMID:23892143
Molecular Function	GO:0005515	protein binding	WDR77	IPI	UniProtKB:Q9Y3Y2	Human	PMID:25284789
Molecular Function	GO:0005515	protein binding	WDR77	IPI	UniProtKB:O14744	Human	PMID:26763441
Molecular Function	GO:0005515	protein binding	WDR77	IPI	UniProtKB:O14744	Human	PMID:26912361
Molecular Function	GO:0005515	protein binding	WDR77	IPI	UniProtKB:O60333-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	WDR77	IPI	UniProtKB:O76024	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	WDR77	IPI	UniProtKB:P04792	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	WDR77	IPI	UniProtKB:P13473-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	WDR77	IPI	UniProtKB:P55212	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	WDR77	IPI	UniProtKB:P62826	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	WDR77	IPI	UniProtKB:Q9Y3C5	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	WDR77	IPI	UniProtKB:Q6ZV65	Human	PMID:33376131
Molecular Function	GO:0005515	protein binding	Wdr77	IPI	PR:E9Q9D5	Mouse	PMID:23055941
Molecular Function	GO:1990756	ubiquitin ligase-substrate adaptor activity	Wdr77	IDA		Mouse	MGI:MGI:7334688|PMID:35197566
Cellular Component	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex	Wdr77	IDA		Mouse	MGI:MGI:7334688|PMID:35197566
Cellular Component	GO:0005737	cytoplasm	WDR77	IGI	UniProtKB:P10275	Human	PMID:12972618
Cellular Component	GO:0005737	cytoplasm	WDR77	IDA		Human	PMID:19188445
Cellular Component	GO:0005829	cytosol	WDR77	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	WDR77	IDA		Human	PMID:18984161
Cellular Component	GO:0005829	cytosol	WDR77	IDA		Human	PMID:21081503
Cellular Component	GO:0005794	Golgi apparatus	WDR77	IDA		Human	GO_REF:0000052
Cellular Component	GO:0034709	methylosome	WDR77	IDA		Human	PMID:11756452
Cellular Component	GO:0034709	methylosome	WDR77	IDA		Human	PMID:18984161
Cellular Component	GO:0034709	methylosome	WDR77	IDA		Human	PMID:25284789
Cellular Component	GO:0005654	nucleoplasm	WDR77	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	WDR77	IGI	UniProtKB:P10275	Human	PMID:12972618
Cellular Component	GO:0005634	nucleus	WDR77	IDA		Human	PMID:21081503
Biological Process	GO:0060767	epithelial cell proliferation involved in prostate gland development	Wdr77	IMP	MGI:MGI:3798419	Mouse	PMID:17032745
Biological Process	GO:0008285	negative regulation of cell population proliferation	Wdr77	IGI	UniProtKB:P10275	Mouse	PMID:18356297
Biological Process	GO:0060770	negative regulation of epithelial cell proliferation involved in prostate gland development	Wdr77	IMP	MGI:MGI:3798419	Mouse	PMID:17032745
Biological Process	GO:0008284	positive regulation of cell population proliferation	Wdr77	IGI	UniProtKB:P10275	Mouse	PMID:18356297
Biological Process	GO:0000209	protein polyubiquitination	Wdr77	IDA		Mouse	MGI:MGI:7334688|PMID:35197566
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	Wdr77	IMP	MGI:MGI:3798419	Mouse	PMID:17032745
Biological Process	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development	Wdr77	IMP	MGI:MGI:3798419	Mouse	PMID:17032745
Biological Process	GO:0006511	ubiquitin-dependent protein catabolic process	Wdr77	IDA		Mouse	MGI:MGI:7334688|PMID:35197566

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern