Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes WDR45
  • Mouse genes Wdr45
  • Rat genes Wdr45
  • Zfish genes wdr45
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Wdr45

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:1901981	phosphatidylinositol phosphate binding	WDR45	IDA		Human	PMID:28561066
Molecular Function	GO:0032266	phosphatidylinositol-3-phosphate binding	WDR45	IDA		Human	PMID:31271352
Molecular Function	GO:0005515	protein binding	WDR45	IPI	UniProtKB:Q2TAZ0	Human	PMID:20562859
Molecular Function	GO:0005515	protein binding	WDR45	IPI	UniProtKB:O75385	Human	PMID:28561066
Molecular Function	GO:0005515	protein binding	WDR45	IPI	UniProtKB:Q2TAZ0	Human	PMID:28561066
Molecular Function	GO:0005515	protein binding	WDR45	IPI	UniProtKB:Q5MNZ9	Human	PMID:28561066
Molecular Function	GO:0005515	protein binding	WDR45	IPI	UniProtKB:Q9Y4P8	Human	PMID:28561066
Molecular Function	GO:0005515	protein binding	WDR45	IPI	UniProtKB:Q2TAZ0	Human	PMID:31412244
Molecular Function	GO:0019901	protein kinase binding	WDR45	IPI	UniProtKB:P54619|UniProtKB:P54646|UniProtKB:Q13131|UniProtKB:Q9Y478	Human	PMID:28561066
Cellular Component	GO:0000407	phagophore assembly site	WDR45	IDA		Human	PMID:28561066
Biological Process	GO:0000045	autophagosome assembly	WDR45	IMP		Human	PMID:28561066
Biological Process	GO:0006914	autophagy	WDR45	IMP		Human	PMID:23435086
Biological Process	GO:0009267	cellular response to starvation	WDR45	IDA		Human	PMID:28561066
Biological Process	GO:2000786	positive regulation of autophagosome assembly	WDR45	IDA		Human	PMID:31271352

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern