Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes WASHC2A,WASHC2C
  • Mouse genes Washc2
  • Rat genes Washc2c
  • Zfish genes washc2c
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Washc2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	WASHC2C	IDA		Human	PMID:20498093
Molecular Function	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	WASHC2C	IDA		Human	PMID:20498093
Molecular Function	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	WASHC2C	IDA		Human	PMID:20498093
Molecular Function	GO:0032266	phosphatidylinositol-3-phosphate binding	WASHC2C	IDA		Human	PMID:20498093
Molecular Function	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	WASHC2C	IDA		Human	PMID:20498093
Molecular Function	GO:0070273	phosphatidylinositol-4-phosphate binding	WASHC2C	IDA		Human	PMID:20498093
Molecular Function	GO:0010314	phosphatidylinositol-5-phosphate binding	WASHC2C	IDA		Human	PMID:20498093
Molecular Function	GO:0005515	protein binding	WASHC2A	IPI	UniProtKB:O60826	Human	PMID:25355947
Molecular Function	GO:0005515	protein binding	WASHC2A	IPI	UniProtKB:Q567U6	Human	PMID:25355947
Molecular Function	GO:0005515	protein binding	WASHC2A	IPI	UniProtKB:Q8K0F1	Human	PMID:29084197
Molecular Function	GO:0005515	protein binding	WASHC2C	IPI	UniProtKB:A8K0Z3	Human	PMID:19922874
Molecular Function	GO:0005515	protein binding	WASHC2C	IPI	UniProtKB:Q5T1M5	Human	PMID:22070227
Molecular Function	GO:0005515	protein binding	WASHC2C	IPI	UniProtKB:Q96QK1	Human	PMID:23331060
Molecular Function	GO:0005515	protein binding	WASHC2C	IPI	UniProtKB:Q9QZ88	Human	PMID:23331060
Molecular Function	GO:0005515	protein binding	WASHC2C	IPI	UniProtKB:O75165	Human	PMID:24643499
Molecular Function	GO:0005515	protein binding	WASHC2C	IPI	UniProtKB:Q96QK1	Human	PMID:24980502
Molecular Function	GO:0005515	protein binding	WASHC2C	IPI	UniProtKB:O60826	Human	PMID:25355947
Molecular Function	GO:0005515	protein binding	WASHC2C	IPI	UniProtKB:Q567U6	Human	PMID:25355947
Molecular Function	GO:0005515	protein binding	WASHC2C	IPI	UniProtKB:Q7Z3J2	Human	PMID:25355947
Molecular Function	GO:1905394	retromer complex binding	WASHC2C	IDA		Human	PMID:23331060
Molecular Function	GO:1905394	retromer complex binding	WASHC2C	IMP		Human	PMID:27385586
Cellular Component	GO:0005829	cytosol	WASHC2A	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	WASHC2C	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005769	early endosome	WASHC2C	IDA		Human	PMID:19922874
Cellular Component	GO:0005768	endosome	WASHC2C	IDA		Human	PMID:20923837
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	WASHC2A	IDA		Human	GO_REF:0000052
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	WASHC2C	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005730	nucleolus	WASHC2A	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005730	nucleolus	WASHC2C	IDA		Human	GO_REF:0000052
Cellular Component	GO:0071203	WASH complex	WASHC2C	IDA		Human	PMID:19922875
Cellular Component	GO:0071203	WASH complex	Washc2	IDA		Mouse	PMID:27390154
Biological Process	GO:0032456	endocytic recycling	WASHC2C	IMP		Human	PMID:25278552
Biological Process	GO:2000813	negative regulation of barbed-end actin filament capping	WASHC2C	IDA		Human	PMID:20498093
Biological Process	GO:0036010	protein localization to endosome	WASHC2A	IMP		Human	PMID:28892079
Biological Process	GO:0036010	protein localization to endosome	WASHC2C	IMP		Human	PMID:28892079
Biological Process	GO:1900024	regulation of substrate adhesion-dependent cell spreading	WASHC2C	IDA		Human	PMID:22070227
Biological Process	GO:0042147	retrograde transport, endosome to Golgi	WASHC2C	IMP		Human	PMID:19922874

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern