Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes VTCN1
  • Mouse genes Vtcn1
  • Rat genes Vtcn1
  • Zfish genes vtcn1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Vtcn1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005102	signaling receptor binding	Vtcn1	IDA		Mouse	PMID:16751379
Molecular Function	GO:0005102	signaling receptor binding	Vtcn1	IGI	MGI:MGI:2658978	Mouse	PMID:15585831
Cellular Component	GO:0009897	external side of plasma membrane	VTCN1	IDA		Human	PMID:16606666
Cellular Component	GO:0009897	external side of plasma membrane	Vtcn1	IDA		Mouse	PMID:17051145
Biological Process	GO:0032633	interleukin-4 production	Vtcn1	IMP	MGI:MGI:3663315	Mouse	PMID:16914726
Biological Process	GO:0043066	negative regulation of apoptotic process	VTCN1	IMP		Human	PMID:15878339
Biological Process	GO:0050868	negative regulation of T cell activation	VTCN1	IMP		Human	PMID:16606666
Biological Process	GO:0050868	negative regulation of T cell activation	Vtcn1	IDA		Mouse	PMID:15585831
Biological Process	GO:0042130	negative regulation of T cell proliferation	VTCN1	IMP		Human	PMID:16606666
Biological Process	GO:0032743	positive regulation of interleukin-2 production	Vtcn1	IMP		Mouse	PMID:16751379
Biological Process	GO:0042102	positive regulation of T cell proliferation	Vtcn1	IMP		Mouse	PMID:16751379
Biological Process	GO:0001562	response to protozoan	Vtcn1	IMP	MGI:MGI:3663315	Mouse	PMID:16914726
Biological Process	GO:0032609	type II interferon production	Vtcn1	IMP	MGI:MGI:3663315	Mouse	PMID:16914726

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern