Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes VPS72
  • Mouse genes Vps72
  • Rat genes Vps72
  • Zfish genes vps72a,vps72b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Vps72

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042393	histone binding	VPS72	IPI	UniProtKB:P06899,UniProtKB:P0C0S5	Human	PMID:26974126
Molecular Function	GO:0042393	histone binding	Vps72	IPI	UniProtKB:P0C0S6	Mouse	MGI:MGI:6287047|PMID:30842416
Molecular Function	GO:0140713	histone chaperone activity	VPS72	IMP		Human	PMID:26974126
Molecular Function	GO:0005515	protein binding	VPS72	IPI	UniProtKB:Q9Y265	Human	PMID:15647280
Molecular Function	GO:0005515	protein binding	VPS72	IPI	UniProtKB:Q99750	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	VPS72	IPI	UniProtKB:Q9Y265	Human	PMID:16230350
Molecular Function	GO:0005515	protein binding	VPS72	IPI	UniProtKB:Q6NT76	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	VPS72	IPI	UniProtKB:Q99750	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	VPS72	IPI	UniProtKB:Q9Y265	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	VPS72	IPI	UniProtKB:O75031	Human	PMID:32296183
Cellular Component	GO:0035267	NuA4 histone acetyltransferase complex	VPS72	IDA		Human	PMID:27153538
Cellular Component	GO:0016607	nuclear speck	VPS72	IDA		Human	GO_REF:0000052
Cellular Component	GO:0000786	nucleosome	VPS72	IDA		Human	PMID:27153538
Cellular Component	GO:0032991	protein-containing complex	VPS72	IDA		Human	PMID:14966270
Biological Process	GO:0043968	histone H2A acetylation	VPS72	IDA		Human	PMID:27153538
Biological Process	GO:0043967	histone H4 acetylation	VPS72	IDA		Human	PMID:27153538
Biological Process	GO:1905168	positive regulation of double-strand break repair via homologous recombination	VPS72	IDA		Human	PMID:27153538
Biological Process	GO:0051726	regulation of cell cycle	VPS72	IMP		Human	PMID:27153538
Biological Process	GO:0035019	somatic stem cell population maintenance	Vps72	IDA		Mouse	PMID:19379700
Biological Process	GO:0045815	transcription initiation-coupled chromatin remodeling	VPS72	IMP	UniProtKB:P06899,UniProtKB:P0C0S5	Human	PMID:26974126

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern