Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes VPS54
  • Mouse genes Vps54
  • Rat genes Vps54
  • Zfish genes vps54
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Vps54

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	VPS54	IPI	UniProtKB:Q8N1B4	Human	PMID:15878329
Molecular Function	GO:0005515	protein binding	VPS54	IPI	UniProtKB:Q9UID3	Human	PMID:20685960
Molecular Function	GO:0005515	protein binding	VPS54	IPI	UniProtKB:Q9UID3	Human	PMID:3172165
Molecular Function	GO:0005515	protein binding	Vps54	IPI	UniProtKB:Q5PPK9	Rat	PMID:27191843|RGD:11344934
Cellular Component	GO:0005737	cytoplasm	Vps54	IDA		Mouse	PMID:19013502
Cellular Component	GO:0000938	GARP complex	VPS54	IDA		Human	PMID:19620288
Cellular Component	GO:0000938	GARP complex	VPS54	IDA		Human	PMID:25799061
Cellular Component	GO:0000938	GARP complex	Vps54	IDA		Mouse	PMID:20615984
Cellular Component	GO:0005794	Golgi apparatus	VPS54	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005794	Golgi apparatus	VPS54	IDA		Human	PMID:15878329
Cellular Component	GO:0016020	membrane	Vps54	IDA		Rat	PMID:3172165|RGD:25671404
Cellular Component	GO:0005739	mitochondrion	Vps54	IMP	MGI:MGI:1857091	Mouse	PMID:22486171
Cellular Component	GO:0005654	nucleoplasm	VPS54	IDA		Human	GO_REF:0000052
Cellular Component	GO:0048471	perinuclear region of cytoplasm	VPS54	IDA		Human	PMID:15878329
Cellular Component	GO:0005802	trans-Golgi network	VPS54	IMP		Human	PMID:25795912
Cellular Component	GO:0005802	trans-Golgi network	VPS54	IDA		Human	PMID:25799061
Cellular Component	GO:0005802	trans-Golgi network	Vps54	IDA		Rat	PMID:25799061|RGD:11053432
Biological Process	GO:0006309	apoptotic DNA fragmentation	Vps54	IMP	MGI:MGI:1857091	Mouse	PMID:11403940
Biological Process	GO:0048708	astrocyte differentiation	Vps54	IMP	MGI:MGI:1857091	Mouse	PMID:29890290
Biological Process	GO:0071393	cellular response to progesterone stimulus	Vps54	IMP	MGI:MGI:1857091	Mouse	PMID:22486171
Biological Process	GO:0010467	gene expression	Vps54	IMP	MGI:MGI:1857091	Mouse	PMID:10739637
Biological Process	GO:0010467	gene expression	Vps54	IMP	MGI:MGI:1857091	Mouse	PMID:12182889
Biological Process	GO:0010467	gene expression	Vps54	IMP	MGI:MGI:1857091	Mouse	PMID:17434459
Biological Process	GO:0010467	gene expression	Vps54	IMP	MGI:MGI:1857091	Mouse	PMID:10952021
Biological Process	GO:0010467	gene expression	Vps54	IMP	MGI:MGI:1857091	Mouse	PMID:19013502
Biological Process	GO:0010467	gene expression	Vps54	IMP	MGI:MGI:1857091	Mouse	PMID:21354103
Biological Process	GO:0010467	gene expression	Vps54	IMP	MGI:MGI:1857091	Mouse	PMID:22486171
Biological Process	GO:0010467	gene expression	Vps54	IMP	MGI:MGI:1857091	Mouse	PMID:23872513
Biological Process	GO:0010467	gene expression	Vps54	IMP	MGI:MGI:1857091	Mouse	PMID:28658628
Biological Process	GO:0010467	gene expression	Vps54	IMP	MGI:MGI:1857091	Mouse	PMID:24141020
Biological Process	GO:0010467	gene expression	Vps54	IMP	MGI:MGI:1857091	Mouse	PMID:29890290
Biological Process	GO:0048872	homeostasis of number of cells	Vps54	IMP	MGI:MGI:1857091	Mouse	PMID:24141020
Biological Process	GO:0048873	homeostasis of number of cells within a tissue	Vps54	IMP	MGI:MGI:1857091	Mouse	PMID:24349357
Biological Process	GO:0048873	homeostasis of number of cells within a tissue	Vps54	IMP	MGI:MGI:1857091	Mouse	PMID:8815872
Biological Process	GO:0001701	in utero embryonic development	Vps54	IMP	MGI:MGI:3613397	Mouse	PMID:16244655
Biological Process	GO:0006874	intracellular calcium ion homeostasis	Vps54	IMP	MGI:MGI:1857091	Mouse	PMID:23872513
Biological Process	GO:0051938	L-glutamate import	Vps54	IMP	MGI:MGI:1857091	Mouse	PMID:20558160
Biological Process	GO:0060173	limb development	Vps54	IMP	MGI:MGI:1857091	Mouse	PMID:24141020
Biological Process	GO:0060173	limb development	Vps54	IMP	MGI:MGI:1857091	Mouse	PMID:32345721
Biological Process	GO:0035108	limb morphogenesis	Vps54	IMP	MGI:MGI:1857091	Mouse	PMID:24141020
Biological Process	GO:0007041	lysosomal transport	VPS54	IMP		Human	PMID:25799061
Biological Process	GO:0014004	microglia differentiation	Vps54	IMP	MGI:MGI:1857091	Mouse	PMID:29890290
Biological Process	GO:0007005	mitochondrion organization	Vps54	IMP	MGI:MGI:1857091	Mouse	PMID:22486171
Biological Process	GO:0061744	motor behavior	Vps54	IMP		Mouse	PMID:29890290
Biological Process	GO:0097049	motor neuron apoptotic process	Vps54	IMP	MGI:MGI:1857091	Mouse	PMID:10952021
Biological Process	GO:0097049	motor neuron apoptotic process	Vps54	IMP	MGI:MGI:1857091	Mouse	PMID:29890290
Biological Process	GO:0050881	musculoskeletal movement	Vps54	IMP	MGI:MGI:1857091	Mouse	PMID:8815872
Biological Process	GO:2000672	negative regulation of motor neuron apoptotic process	Vps54	IMP	MGI:MGI:1857091	Mouse	PMID:16244655
Biological Process	GO:0097719	neural tissue regeneration	Vps54	IMP		Mouse	PMID:24141020
Biological Process	GO:0060052	neurofilament cytoskeleton organization	Vps54	IMP	MGI:MGI:1857091	Mouse	PMID:11493023
Biological Process	GO:0150076	neuroinflammatory response	Vps54	IMP	MGI:MGI:1857091	Mouse	PMID:29890290
Biological Process	GO:0007274	neuromuscular synaptic transmission	Vps54	IMP	MGI:MGI:1857091	Mouse	PMID:24349357
Biological Process	GO:0051402	neuron apoptotic process	Vps54	IMP	MGI:MGI:1857091	Mouse	PMID:20558160
Biological Process	GO:0051402	neuron apoptotic process	Vps54	IMP	MGI:MGI:1857091	Mouse	PMID:32345721
Biological Process	GO:0048812	neuron projection morphogenesis	Vps54	IMP	MGI:MGI:1857091	Mouse	PMID:20558160
Biological Process	GO:0035128	post-embryonic forelimb morphogenesis	Vps54	IMP	MGI:MGI:1857091	Mouse	PMID:11403940
Biological Process	GO:0008104	protein localization	Vps54	IMP	MGI:MGI:1857091	Mouse	PMID:19013502
Biological Process	GO:0034394	protein localization to cell surface	Vps54	IMP	MGI:MGI:1857091	Mouse	PMID:23708095
Biological Process	GO:0045047	protein targeting to ER	Vps54	IMP	MGI:MGI:1857091	Mouse	PMID:28658628
Biological Process	GO:0045047	protein targeting to ER	Vps54	IMP	MGI:MGI:1857091	Mouse	PMID:32345721
Biological Process	GO:0006622	protein targeting to lysosome	Vps54	IMP	MGI:MGI:1857091	Mouse	PMID:28658628
Biological Process	GO:0006622	protein targeting to lysosome	Vps54	IMP	MGI:MGI:1857091	Mouse	PMID:32345721
Biological Process	GO:0006623	protein targeting to vacuole	Vps54	IMP	MGI:MGI:1857091	Mouse	PMID:23708095
Biological Process	GO:0040008	regulation of growth	Vps54	IMP	MGI:MGI:1857091	Mouse	PMID:8815872
Biological Process	GO:0022904	respiratory electron transport chain	Vps54	IMP	MGI:MGI:1857091	Mouse	PMID:22486171
Biological Process	GO:0046677	response to antibiotic	Vps54	IMP	MGI:MGI:1857091	Mouse	PMID:32345721
Biological Process	GO:0051592	response to calcium ion	Vps54	IMP	MGI:MGI:1857091	Mouse	PMID:10739637
Biological Process	GO:0042147	retrograde transport, endosome to Golgi	VPS54	IMP		Human	PMID:25799061
Biological Process	GO:0007519	skeletal muscle tissue development	Vps54	IMP	MGI:MGI:1857091	Mouse	PMID:11403940
Biological Process	GO:0048630	skeletal muscle tissue growth	Vps54	IMP	MGI:MGI:1857091	Mouse	PMID:23872513
Biological Process	GO:0048515	spermatid differentiation	Vps54	IMP	MGI:MGI:1857091	Mouse	PMID:16244655
Biological Process	GO:0030149	sphingolipid catabolic process	Vps54	IMP	MGI:MGI:1857091	Mouse	PMID:32345721
Biological Process	GO:0006941	striated muscle contraction	Vps54	IMP	MGI:MGI:1857091	Mouse	PMID:10739637
Biological Process	GO:0006941	striated muscle contraction	Vps54	IMP	MGI:MGI:1857091	Mouse	PMID:23872513
Biological Process	GO:0051932	synaptic transmission, GABAergic	Vps54	IMP	MGI:MGI:1857091	Mouse	PMID:20643756
Biological Process	GO:0035249	synaptic transmission, glutamatergic	Vps54	IMP	MGI:MGI:1857091	Mouse	PMID:29890290
Biological Process	GO:0070493	thrombin-activated receptor signaling pathway	Vps54	IMP	MGI:MGI:1857091	Mouse	PMID:10952021
Biological Process	GO:0010992	ubiquitin recycling	Vps54	IMP	MGI:MGI:1857091	Mouse	PMID:19013502
Biological Process	GO:0007033	vacuole organization	Vps54	IMP	MGI:MGI:1857091	Mouse	PMID:11403940
Biological Process	GO:0090119	vesicle-mediated cholesterol transport	Vps54	IMP	MGI:MGI:1857091	Mouse	PMID:28658628

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern