Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes VPS45
  • Mouse genes Vps45
  • Rat genes Vps45
  • Zfish genes vps45
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Vps45

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	VPS45	IPI	UniProtKB:Q9H1K0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	VPS45	IPI	UniProtKB:Q9H1K0	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	VPS45	IPI	UniProtKB:O14662-5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Vps45	IPI	PR:Q8R307	Mouse	PMID:14668490
Molecular Function	GO:0005515	protein binding	Vps45	IPI	UniProtKB:Q63635	Mouse	PMID:9045632
Molecular Function	GO:0005515	protein binding	Vps45	IPI	RGD:1311556	Rat	PMID:14668490|RGD:1549677
Molecular Function	GO:0005515	protein binding	Vps45	IPI	UniProtKB:Q8BVI5	Rat	PMID:18337752|RGD:8553871
Molecular Function	GO:0005515	protein binding	Vps45	IPI	UniProtKB:Q63635	Rat	PMID:9243506|RGD:8553703
Cellular Component	GO:0010008	endosome membrane	Vps45	IDA		Mouse	PMID:9045632
Cellular Component	GO:0005794	Golgi apparatus	Vps45	IDA		Rat	PMID:9243506|RGD:8553703
Cellular Component	GO:0000139	Golgi membrane	Vps45	IDA		Mouse	PMID:9045632
Cellular Component	GO:0016020	membrane	Vps45	IDA		Rat	PMID:9243506|RGD:8553703
Cellular Component	GO:0008021	synaptic vesicle	Vps45	IDA		Rat	PMID:23622064|RGD:13702180
Biological Process	GO:1902746	regulation of lens fiber cell differentiation	vps45	IMP	ZFIN:ZDB-GENO-190211-1	Zfish	PMID:30322969

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern