Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes USP50
  • Mouse genes Usp50
  • Rat genes Usp50
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Usp50

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	Usp50	IPI	UniProtKB:Q9ULZ3	Mouse	PMID:28094437
Molecular Function	GO:0019783	ubiquitin-like protein peptidase activity	USP50	IDA		Human	PMID:28094437
Biological Process	GO:0035063	nuclear speck organization	USP50	IMP		Human	PMID:28094437
Biological Process	GO:2001056	positive regulation of cysteine-type endopeptidase activity	USP50	IMP		Human	PMID:28094437
Biological Process	GO:2001056	positive regulation of cysteine-type endopeptidase activity	Usp50	IMP		Mouse	PMID:28094437
Biological Process	GO:0032731	positive regulation of interleukin-1 beta production	USP50	IMP		Human	PMID:28094437
Biological Process	GO:0032731	positive regulation of interleukin-1 beta production	Usp50	IMP		Mouse	PMID:28094437
Biological Process	GO:0032741	positive regulation of interleukin-18 production	Usp50	IMP		Mouse	PMID:28094437
Biological Process	GO:1900227	positive regulation of NLRP3 inflammasome complex assembly	USP50	IMP		Human	PMID:28094437
Biological Process	GO:1900227	positive regulation of NLRP3 inflammasome complex assembly	Usp50	IMP		Mouse	PMID:28094437
Biological Process	GO:0016579	protein deubiquitination	USP50	IDA		Human	PMID:28094437

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern