Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes UROS
  • Mouse genes Uros
  • Rat genes Uros
  • Zfish genes uros
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Uros

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005542	folic acid binding	Uros	IDA		Rat	PMID:6466301|RGD:2303402
Molecular Function	GO:0004852	uroporphyrinogen-III synthase activity	UROS	IDA		Human	PMID:18004775
Molecular Function	GO:0004852	uroporphyrinogen-III synthase activity	UROS	IDA		Human	PMID:3174619
Molecular Function	GO:0004852	uroporphyrinogen-III synthase activity	UROS	IDA		Human	PMID:3805019
Molecular Function	GO:0004852	uroporphyrinogen-III synthase activity	Uros	IDA		Mouse	PMID:7607680
Molecular Function	GO:0004852	uroporphyrinogen-III synthase activity	Uros	IMP	MGI:MGI:3620007	Mouse	MGI:MGI:3620006
Molecular Function	GO:0004852	uroporphyrinogen-III synthase activity	Uros	IDA		Rat	PMID:6604545|RGD:2303403
Cellular Component	GO:0005829	cytosol	Uros	IDA		Rat	PMID:6466301|RGD:2303402
Cellular Component	GO:0005739	mitochondrion	Uros	HDA		Mouse	PMID:14651853
Biological Process	GO:0071418	cellular response to amine stimulus	Uros	IEP		Rat	PMID:10416273|RGD:2303399
Biological Process	GO:0071243	cellular response to arsenic-containing substance	Uros	IEP		Rat	PMID:10416273|RGD:2303399
Biological Process	GO:0006783	heme biosynthetic process	UROS	IDA		Human	PMID:3805019
Biological Process	GO:0006779	porphyrin-containing compound biosynthetic process	Uros	IMP	MGI:MGI:3620007	Mouse	MGI:MGI:3620006
Biological Process	GO:0006779	porphyrin-containing compound biosynthetic process	Uros	IDA		Mouse	PMID:7607680
Biological Process	GO:0046677	response to antibiotic	Uros	IEP		Rat	PMID:9253145|RGD:2303401
Biological Process	GO:0070541	response to platinum ion	Uros	IEP		Rat	PMID:925603|RGD:4144822
Biological Process	GO:0006780	uroporphyrinogen III biosynthetic process	UROS	IDA		Human	PMID:18004775
Biological Process	GO:0006780	uroporphyrinogen III biosynthetic process	UROS	IDA		Human	PMID:3174619
Biological Process	GO:0006780	uroporphyrinogen III biosynthetic process	UROS	IDA		Human	PMID:3805019
Biological Process	GO:0006780	uroporphyrinogen III biosynthetic process	Uros	IDA		Rat	PMID:17763925|RGD:4144811

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern