Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes UBA2
  • Mouse genes Uba2
  • Rat genes Uba2
  • Zfish genes uba2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Uba2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005524	ATP binding	UBA2	IMP		Human	PMID:15660128
Molecular Function	GO:0000287	magnesium ion binding	UBA2	IMP		Human	PMID:15660128
Molecular Function	GO:0005515	protein binding	UBA2	IPI	UniProtKB:Q9UBE0	Human	PMID:10187858
Molecular Function	GO:0005515	protein binding	UBA2	IPI	UniProtKB:Q9UBE0	Human	PMID:15660128
Molecular Function	GO:0005515	protein binding	UBA2	IPI	UniProtKB:Q99497	Human	PMID:15983381
Molecular Function	GO:0005515	protein binding	UBA2	IPI	UniProtKB:Q9UBE0	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	UBA2	IPI	UniProtKB:P63279	Human	PMID:17643372
Molecular Function	GO:0005515	protein binding	UBA2	IPI	UniProtKB:P63165	Human	PMID:20164921
Molecular Function	GO:0005515	protein binding	UBA2	IPI	UniProtKB:Q9UBE0	Human	PMID:20164921
Molecular Function	GO:0005515	protein binding	UBA2	IPI	UniProtKB:G2XKQ0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	UBA2	IPI	UniProtKB:P63165	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	UBA2	IPI	UniProtKB:P63279	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	UBA2	IPI	UniProtKB:Q9UBE0	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	UBA2	IPI	UniProtKB:P63279	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	UBA2	IPI	UniProtKB:Q9UBE0	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	UBA2	IPI	UniProtKB:P63165	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	UBA2	IPI	UniProtKB:Q9UBE0	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	UBA2	IPI	UniProtKB:P63165	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	UBA2	IPI	UniProtKB:Q6FHY5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Uba2	IPI	PR:O08900	Mouse	PMID:15767674
Molecular Function	GO:0046982	protein heterodimerization activity	UBA2	IPI	UniProtKB:Q9UBE0	Human	PMID:20164921
Molecular Function	GO:0044388	small protein activating enzyme binding	UBA2	IPI	UniProtKB:Q9UBE0	Human	PMID:15660128
Molecular Function	GO:0019948	SUMO activating enzyme activity	UBA2	IDA		Human	PMID:10187858
Molecular Function	GO:0019948	SUMO activating enzyme activity	UBA2	IDA		Human	PMID:20164921
Molecular Function	GO:0019948	SUMO activating enzyme activity	Uba2	IDA		Mouse	PMID:21554500
Molecular Function	GO:0032183	SUMO binding	UBA2	IPI	UniProtKB:P63165	Human	PMID:15660128
Molecular Function	GO:0008134	transcription factor binding	Uba2	IPI	PR:Q03267	Mouse	PMID:15767674
Molecular Function	GO:0044390	ubiquitin-like protein conjugating enzyme binding	UBA2	IPI	UniProtKB:P63279	Human	PMID:15660128
Cellular Component	GO:0005654	nucleoplasm	UBA2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0031510	SUMO activating enzyme complex	UBA2	IDA		Human	PMID:10187858
Cellular Component	GO:0031510	SUMO activating enzyme complex	UBA2	IDA		Human	PMID:15660128
Cellular Component	GO:0031510	SUMO activating enzyme complex	UBA2	IDA		Human	PMID:20164921
Biological Process	GO:0033235	positive regulation of protein sumoylation	UBA2	IDA		Human	PMID:10187858
Biological Process	GO:0016925	protein sumoylation	UBA2	IMP		Human	PMID:15660128
Biological Process	GO:0016925	protein sumoylation	UBA2	IDA		Human	PMID:20164921
Biological Process	GO:0016925	protein sumoylation	UBA2	IMP		Human	PMID:21968017

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern