Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TUBB2B
  • Mouse genes Tubb2b
  • Rat genes Tubb2b
  • Zfish genes tubb2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tubb2b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	TUBB2B	IPI	UniProtKB:O00555	Human	PMID:21078624
Molecular Function	GO:0046982	protein heterodimerization activity	TUBB2B	IDA		Human	PMID:23001566
Molecular Function	GO:0046982	protein heterodimerization activity	TUBB2B	IDA		Human	PMID:26732629
Molecular Function	GO:0046982	protein heterodimerization activity	TUBB2B	IDA		Human	PMID:28013290
Cellular Component	GO:0045171	intercellular bridge	TUBB2B	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005874	microtubule	TUBB2B	IDA		Human	PMID:21525035
Cellular Component	GO:0015630	microtubule cytoskeleton	TUBB2B	IDA		Human	GO_REF:0000052
Cellular Component	GO:0015630	microtubule cytoskeleton	TUBB2B	IDA		Human	PMID:23001566
Cellular Component	GO:0015630	microtubule cytoskeleton	TUBB2B	IDA		Human	PMID:28013290
Cellular Component	GO:0072686	mitotic spindle	TUBB2B	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	TUBB2B	HDA		Human	PMID:21630459
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Tubb2b	IDA		Mouse	PMID:27594048
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Tubb2b	IMP		Mouse	PMID:27594048
Biological Process	GO:0021987	cerebral cortex development	Tubb2b	IMP	MGI:MGI:6506266	Mouse	PMID:31386652
Biological Process	GO:1990403	embryonic brain development	Tubb2b	IMP	MGI:5056364	Mouse	PMID:21515572
Biological Process	GO:0007017	microtubule-based process	TUBB2B	IMP		Human	PMID:26732629
Biological Process	GO:0050804	modulation of chemical synaptic transmission	Tubb2b	IDA		Mouse	PMID:27594048
Biological Process	GO:0050804	modulation of chemical synaptic transmission	Tubb2b	IMP		Mouse	PMID:27594048
Biological Process	GO:0001764	neuron migration	TUBB2B	IMP		Human	PMID:19465910
Biological Process	GO:0001764	neuron migration	Tubb2b	IMP		Rat	PMID:19465910|RGD:8554405
Biological Process	GO:1902669	positive regulation of axon guidance	TUBB2B	IMP		Human	PMID:23001566

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern