Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TUBB2A
  • Mouse genes Tubb2a
  • Rat genes Tubb2a
  • Zfish genes tubb2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tubb2a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	TUBB2A	IPI	UniProtKB:Q96AP0	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	TUBB2A	IPI	UniProtKB:Q5S007	Human	PMID:24275654
Molecular Function	GO:0005515	protein binding	TUBB2A	IPI	UniProtKB:P05412	Human	PMID:25609649
Molecular Function	GO:0005515	protein binding	TUBB2A	IPI	UniProtKB:Q5S007	Human	PMID:31046837
Molecular Function	GO:0005515	protein binding	TUBB2A	IPI	UniProtKB:P05412	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	TUBB2A	IPI	UniProtKB:P08247	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	TUBB2A	IPI	UniProtKB:P55212	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	TUBB2A	IPI	UniProtKB:Q14457	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	TUBB2A	IPI	UniProtKB:Q96MN9-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	TUBB2A	IPI	UniProtKB:P00533	Human	PMID:35384245
Cellular Component	GO:0070062	extracellular exosome	TUBB2A	HDA		Human	PMID:19056867
Cellular Component	GO:1903561	extracellular vesicle	TUBB2A	HDA		Human	PMID:24769233
Cellular Component	GO:0045171	intercellular bridge	TUBB2A	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005874	microtubule	TUBB2A	IDA		Human	PMID:21525035
Cellular Component	GO:0015630	microtubule cytoskeleton	TUBB2A	IDA		Human	GO_REF:0000052
Cellular Component	GO:0072686	mitotic spindle	TUBB2A	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	TUBB2A	HDA		Human	PMID:21630459
Biological Process	GO:0021987	cerebral cortex development	Tubb2a	IMP	MGI:MGI:6506264	Mouse	PMID:31386652

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern