Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TSPAN15
  • Mouse genes Tspan15
  • Rat genes Tspan15
  • Zfish genes tspan15
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tspan15

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019899	enzyme binding	TSPAN15	IPI	UniProtKB:O14672	Human	PMID:23091066
Molecular Function	GO:0019899	enzyme binding	Tspan15	IPI	UniProtKB:Q10741	Mouse	MGI:MGI:5567902|PMID:23035126
Molecular Function	GO:0005515	protein binding	TSPAN15	IPI	UniProtKB:O14672	Human	PMID:23091066
Molecular Function	GO:0005515	protein binding	TSPAN15	IPI	UniProtKB:Q8N205	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TSPAN15	IPI	UniProtKB:O14672	Human	PMID:26686862
Molecular Function	GO:0005515	protein binding	TSPAN15	IPI	UniProtKB:P04921	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TSPAN15	IPI	UniProtKB:P0DN84	Human	PMID:32296183
Cellular Component	GO:0030054	cell junction	TSPAN15	IDA		Human	GO_REF:0000052
Cellular Component	GO:0009986	cell surface	Tspan15	IDA		Mouse	MGI:MGI:5567902|PMID:23035126
Cellular Component	GO:0005829	cytosol	TSPAN15	IDA		Human	GO_REF:0000052
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	TSPAN15	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016604	nuclear body	TSPAN15	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	TSPAN15	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	TSPAN15	IDA		Human	PMID:23091066
Cellular Component	GO:0005886	plasma membrane	TSPAN15	IDA		Human	PMID:30463011
Cellular Component	GO:0005886	plasma membrane	Tspan15	IDA		Mouse	MGI:MGI:6316557|PMID:30463011
Cellular Component	GO:0097197	tetraspanin-enriched microdomain	Tspan15	IDA		Mouse	MGI:MGI:5567902|PMID:23035126
Biological Process	GO:0045746	negative regulation of Notch signaling pathway	TSPAN15	IDA		Human	PMID:30463011
Biological Process	GO:0072659	protein localization to plasma membrane	TSPAN15	IMP		Human	PMID:23091066
Biological Process	GO:0051604	protein maturation	TSPAN15	IMP		Human	PMID:23091066
Biological Process	GO:0051604	protein maturation	Tspan15	IMP		Mouse	MGI:MGI:5567902|PMID:23035126

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern