Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TRPC4AP
  • Mouse genes Trpc4ap
  • Rat genes Trpc4ap
  • Zfish genes trpc4apa,trpc4apb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Trpc4ap

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019902	phosphatase binding	TRPC4AP	IDA		Human	PMID:19389623
Molecular Function	GO:0005515	protein binding	TRPC4AP	IPI	UniProtKB:P62136	Human	PMID:19389623
Molecular Function	GO:0005515	protein binding	TRPC4AP	IPI	UniProtKB:P01106	Human	PMID:20551172
Molecular Function	GO:1990756	ubiquitin ligase-substrate adaptor activity	TRPC4AP	IDA		Human	PMID:29779948
Cellular Component	GO:0080008	Cul4-RING E3 ubiquitin ligase complex	TRPC4AP	IDA		Human	PMID:29779948
Cellular Component	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex	TRPC4AP	IDA		Human	PMID:20551172
Biological Process	GO:0048820	hair follicle maturation	Trpc4ap	IMP	MGI:MGI:4362238	Mouse	PMID:25340873
Biological Process	GO:0016567	protein ubiquitination	TRPC4AP	IDA		Human	PMID:20551172
Biological Process	GO:0006511	ubiquitin-dependent protein catabolic process	TRPC4AP	IDA		Human	PMID:20551172
Biological Process	GO:0140627	ubiquitin-dependent protein catabolic process via the C-end degron rule pathway	TRPC4AP	IDA		Human	PMID:29779948

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern