Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TRMT10A
  • Mouse genes Trmt10a
  • Rat genes Trmt10a
  • Zfish genes trmt10a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Trmt10a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	TRMT10A	IPI	UniProtKB:Q9C029	Human	PMID:32296183
Molecular Function	GO:0003723	RNA binding	TRMT10A	HDA		Human	PMID:22658674
Molecular Function	GO:0052905	tRNA (guanine(9)-N(1))-methyltransferase activity	TRMT10A	IMP		Human	PMID:32392304
Molecular Function	GO:0009019	tRNA (guanine-N1-)-methyltransferase activity	TRMT10A	IDA		Human	PMID:23042678
Molecular Function	GO:0000049	tRNA binding	TRMT10A	IDA		Human	PMID:25053765
Cellular Component	GO:0015629	actin cytoskeleton	TRMT10A	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	TRMT10A	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	TRMT10A	IDA		Human	PMID:23042678
Cellular Component	GO:0070062	extracellular exosome	TRMT10A	HDA		Human	PMID:19056867
Cellular Component	GO:0005730	nucleolus	TRMT10A	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005730	nucleolus	TRMT10A	IDA		Human	PMID:24204302
Cellular Component	GO:0005654	nucleoplasm	TRMT10A	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	TRMT10A	IDA		Human	PMID:24204302
Biological Process	GO:0010960	magnesium ion homeostasis	Trmt10a	IMP	MGI:MGI:4432852	Mouse	PMID:23870131
Biological Process	GO:0030488	tRNA methylation	TRMT10A	IDA		Human	PMID:25053765
Biological Process	GO:0002939	tRNA N1-guanine methylation	TRMT10A	IMP		Human	PMID:32392304

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern