Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TRIP12
  • Mouse genes Trip12
  • Rat genes Trip12
  • Zfish genes trip12
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Trip12

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0046966	nuclear thyroid hormone receptor binding	TRIP12	IDA		Human	PMID:7776974
Molecular Function	GO:0005515	protein binding	TRIP12	IPI	UniProtKB:Q13564	Human	PMID:18627766
Molecular Function	GO:0005515	protein binding	TRIP12	IPI	UniProtKB:Q93009	Human	PMID:19615732
Molecular Function	GO:0005515	protein binding	TRIP12	IPI	UniProtKB:P01106	Human	PMID:20208519
Molecular Function	GO:0005515	protein binding	TRIP12	IPI	UniProtKB:P06748-1	Human	PMID:20208519
Molecular Function	GO:0005515	protein binding	TRIP12	IPI	UniProtKB:Q8N726	Human	PMID:20208519
Molecular Function	GO:0005515	protein binding	TRIP12	IPI	UniProtKB:P49286	Human	PMID:26514267
Molecular Function	GO:0005515	protein binding	TRIP12	IPI	UniProtKB:Q93009	Human	PMID:35044719
Molecular Function	GO:0061630	ubiquitin protein ligase activity	TRIP12	IDA		Human	PMID:18627766
Molecular Function	GO:0061630	ubiquitin protein ligase activity	TRIP12	IMP		Human	PMID:19028681
Molecular Function	GO:0061630	ubiquitin protein ligase activity	TRIP12	IDA		Human	PMID:20208519
Molecular Function	GO:0061630	ubiquitin protein ligase activity	TRIP12	IDA		Human	PMID:30982744
Cellular Component	GO:0016607	nuclear speck	TRIP12	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	TRIP12	IDA		Human	PMID:20208519
Cellular Component	GO:0005634	nucleus	TRIP12	HDA		Human	PMID:21630459
Biological Process	GO:0140861	DNA repair-dependent chromatin remodeling	TRIP12	IMP		Human	PMID:22884692
Biological Process	GO:2000780	negative regulation of double-strand break repair	TRIP12	IMP		Human	PMID:22884692
Biological Process	GO:1901315	negative regulation of histone H2A K63-linked ubiquitination	TRIP12	IMP		Human	PMID:22884692
Biological Process	GO:0000209	protein polyubiquitination	TRIP12	IDA		Human	PMID:30982744
Biological Process	GO:0045995	regulation of embryonic development	Trip12	IMP		Mouse	MGI:MGI:5303027|PMID:22028794
Biological Process	GO:0006511	ubiquitin-dependent protein catabolic process	TRIP12	IDA		Human	PMID:18627766
Biological Process	GO:0006511	ubiquitin-dependent protein catabolic process	TRIP12	IMP		Human	PMID:19028681
Biological Process	GO:0006511	ubiquitin-dependent protein catabolic process	TRIP12	IDA		Human	PMID:20208519
Biological Process	GO:0006511	ubiquitin-dependent protein catabolic process	TRIP12	IDA		Human	PMID:30982744

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern