Comparative GO Graph (mouse, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes
  • Mouse genes Trem3
  • Rat genes Trem3
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Trem3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	Trem3	IPI	UniProtKB:Q6X9T7	Mouse	PMID:11754004
Biological Process	GO:0016477	cell migration	Trem3	IGI	MGI:MGI:1930005	Mouse	PMID:23241959
Biological Process	GO:0032602	chemokine production	Trem3	IGI	MGI:MGI:1930005	Mouse	PMID:23241959
Biological Process	GO:0001816	cytokine production	Trem3	IGI	MGI:MGI:1930005	Mouse	PMID:23241959
Biological Process	GO:0002367	cytokine production involved in immune response	Trem3	IGI	MGI:MGI:1930005	Mouse	PMID:23241959
Biological Process	GO:0030593	neutrophil chemotaxis	Trem3	IGI	MGI:MGI:1930005	Mouse	PMID:23241959
Biological Process	GO:0072672	neutrophil extravasation	Trem3	IGI	MGI:MGI:1930005	Mouse	PMID:23241959
Biological Process	GO:0070945	neutrophil-mediated killing of gram-negative bacterium	Trem3	IGI	MGI:MGI:1930005	Mouse	PMID:23241959
Biological Process	GO:0045089	positive regulation of innate immune response	Trem3	IDA		Mouse	MGI:MGI:2157214|PMID:11754004

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern