Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TRAM1
  • Mouse genes Tram1
  • Rat genes Tram1
  • Zfish genes tram1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tram1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	TRAM1	IPI	UniProtKB:P51572	Human	PMID:18555783
Molecular Function	GO:0005515	protein binding	TRAM1	IPI	UniProtKB:P60468	Human	PMID:19121997
Molecular Function	GO:0005515	protein binding	TRAM1	IPI	UniProtKB:Q02747	Human	PMID:32296183
Cellular Component	GO:0005783	endoplasmic reticulum	TRAM1	IDA		Human	PMID:18555783
Cellular Component	GO:0005789	endoplasmic reticulum membrane	TRAM1	IDA		Human	PMID:12475939
Cellular Component	GO:0005789	endoplasmic reticulum membrane	TRAM1	IDA		Human	PMID:8616892
Cellular Component	GO:0005789	endoplasmic reticulum membrane	TRAM1	IDA		Human	PMID:9506517
Cellular Component	GO:0005789	endoplasmic reticulum membrane	Tram1	IDA		Mouse	MGI:MGI:6162392|PMID:21237175
Biological Process	GO:0006613	cotranslational protein targeting to membrane	TRAM1	IDA		Human	PMID:8616892
Biological Process	GO:0006613	cotranslational protein targeting to membrane	TRAM1	IDA		Human	PMID:9506517
Biological Process	GO:0061371	determination of heart left/right asymmetry	tram1	IMP	ZFIN:ZDB-MRPHLNO-191114-2	Zfish	PMID:31075101
Biological Process	GO:0045048	protein insertion into ER membrane	TRAM1	IDA		Human	PMID:8616892
Biological Process	GO:0006986	response to unfolded protein	TRAM1	IMP		Human	PMID:20430023

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern