Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TPRN
  • Mouse genes Tprn
  • Rat genes Tprn
  • Zfish genes tprn
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tprn

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	TPRN	IPI	UniProtKB:P62136	Human	PMID:22321011
Molecular Function	GO:0005515	protein binding	TPRN	IPI	UniProtKB:P62136	Human	PMID:28330616
Molecular Function	GO:0005515	protein binding	Tprn	IPI	PR:Q3TYR5	Mouse	PMID:30380417
Cellular Component	GO:0032420	stereocilium	Tprn	IDA		Mouse	MGI:MGI:4440409|PMID:20170899
Cellular Component	GO:0032420	stereocilium	Tprn	IDA		Mouse	MGI:MGI:5789047|PMID:27269051
Cellular Component	GO:0120044	stereocilium base	Tprn	IDA		Mouse	PMID:30380417
Cellular Component	GO:0120044	stereocilium base	Tprn	IDA		Mouse	PMID:28209736
Biological Process	GO:0060088	auditory receptor cell stereocilium organization	Tprn	IGI	MGI:MGI:2685697	Mouse	PMID:30380417
Biological Process	GO:0007605	sensory perception of sound	TPRN	IMP		Human	PMID:20170898
Biological Process	GO:0007605	sensory perception of sound	TPRN	IMP		Human	PMID:20170899
Biological Process	GO:0007605	sensory perception of sound	Tprn	IMP	MGI:MGI:5897817	Mouse	PMID:27693694
Biological Process	GO:0007605	sensory perception of sound	Tprn	IMP	MGI:MGI:6281115	Mouse	PMID:30380417
Biological Process	GO:0120045	stereocilium maintenance	Tprn	IMP	MGI:MGI:5897817	Mouse	PMID:27693694

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern