Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TPBG
  • Mouse genes Tpbg
  • Rat genes Tpbg
  • Zfish genes tpbga,tpbgb,tpbgl
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tpbg

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Cellular Component	GO:0043679	axon terminus	Tpbg	IDA		Mouse	PMID:31891182
Cellular Component	GO:0009986	cell surface	TPBG	HDA		Human	PMID:19581412
Cellular Component	GO:0005737	cytoplasm	Tpbg	IDA		Mouse	PMID:15977177
Cellular Component	GO:0030425	dendrite	Tpbg	IDA		Mouse	PMID:31891182
Cellular Component	GO:0005783	endoplasmic reticulum	Tpbg	IDA		Mouse	PMID:15977177
Cellular Component	GO:0005886	plasma membrane	Tpbg	IDA		Mouse	PMID:31891182
Cellular Component	GO:0005886	plasma membrane	Tpbg	IMP	MGI:MGI:4459319	Mouse	PMID:20376365
Cellular Component	GO:0005886	plasma membrane	tpbga	IDA		Zfish	PMID:22100263
Biological Process	GO:0060326	cell chemotaxis	Tpbg	IMP	MGI:MGI:4459319	Mouse	PMID:20376365
Biological Process	GO:0060028	convergent extension involved in axis elongation	tpbga	IGI	ZFIN:ZDB-GENE-980526-87	Zfish	PMID:22100263
Biological Process	GO:0140059	dendrite arborization	Tpbg	IMP	MGI:MGI:4459319	Mouse	PMID:27488640
Biological Process	GO:0140059	dendrite arborization	Tpbg	IMP	MGI:MGI:4459319	Mouse	PMID:22323733
Biological Process	GO:0090497	mesenchymal cell migration	Tpbg	IMP	MGI:MGI:4459319	Mouse	PMID:17507657
Biological Process	GO:0090090	negative regulation of canonical Wnt signaling pathway	tpbga	IMP	ZFIN:ZDB-MRPHLNO-120207-7	Zfish	PMID:22100263
Biological Process	GO:0060829	negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation	tpbga	IGI	ZFIN:ZDB-GENE-980605-30	Zfish	PMID:22100263
Biological Process	GO:0060829	negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation	tpbga	IMP	ZFIN:ZDB-MRPHLNO-120207-7	Zfish	PMID:22100263
Biological Process	GO:0008285	negative regulation of cell population proliferation	Tpbg	IGI	MGI:MGI:103556	Mouse	PMID:22956548
Biological Process	GO:0008285	negative regulation of cell population proliferation	Tpbg	IGI	MGI:MGI:109562	Mouse	PMID:22956548
Biological Process	GO:2000054	negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification	tpbga	IGI	ZFIN:ZDB-GENE-980605-30	Zfish	PMID:22100263
Biological Process	GO:2000054	negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification	tpbga	IMP	ZFIN:ZDB-MRPHLNO-120207-7	Zfish	PMID:22100263
Biological Process	GO:0008355	olfactory learning	Tpbg	IMP	MGI:MGI:4459319	Mouse	PMID:27488640
Biological Process	GO:0050921	positive regulation of chemotaxis	Tpbg	IGI	MGI:MGI:103556	Mouse	PMID:22956548
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	Tpbg	IGI	MGI:MGI:109563	Mouse	PMID:20376365
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	Tpbg	IGI	MGI:MGI:103556	Mouse	PMID:22956548
Biological Process	GO:2000052	positive regulation of non-canonical Wnt signaling pathway	tpbga	IMP	ZFIN:ZDB-MRPHLNO-120207-7	Zfish	PMID:22100263
Biological Process	GO:0051897	positive regulation of protein kinase B signaling	Tpbg	IGI	MGI:MGI:103556	Mouse	PMID:22956548
Biological Process	GO:0051965	positive regulation of synapse assembly	Tpbg	IDA		Mouse	PMID:24613359
Biological Process	GO:0072659	protein localization to plasma membrane	Tpbg	IMP	MGI:MGI:4459319	Mouse	PMID:20376365
Biological Process	GO:0051932	synaptic transmission, GABAergic	Tpbg	IMP	MGI:MGI:4459319	Mouse	PMID:27488640

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern