Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TOP3B
  • Mouse genes Top3b
  • Rat genes Top3b
  • Zfish genes top3b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Top3b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	TOP3B	IPI	UniProtKB:Q6UY14-3	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TOP3B	IPI	UniProtKB:Q7Z698	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TOP3B	IPI	UniProtKB:Q8WV44	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TOP3B	IPI	UniProtKB:Q9UJV3-2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TOP3B	IPI	UniProtKB:Q9UL42	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TOP3B	IPI	UniProtKB:Q9Y2D8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TOP3B	IPI	UniProtKB:Q9H7E2-3	Human	PMID:28176834
Molecular Function	GO:0005515	protein binding	TOP3B	IPI	UniProtKB:Q7Z698	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	TOP3B	IPI	UniProtKB:Q8WV44	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	TOP3B	IPI	UniProtKB:Q9Y2D8	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	TOP3B	IPI	UniProtKB:O76071	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TOP3B	IPI	UniProtKB:P15622-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TOP3B	IPI	UniProtKB:Q14296	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TOP3B	IPI	UniProtKB:Q63ZY3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TOP3B	IPI	UniProtKB:Q6PI77	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TOP3B	IPI	UniProtKB:Q9UJV3-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TOP3B	IPI	UniProtKB:Q9Y2T1	Human	PMID:32296183
Molecular Function	GO:0003723	RNA binding	TOP3B	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	TOP3B	HDA		Human	PMID:22681889
Cellular Component	GO:0000793	condensed chromosome	Top3b	IDA		Mouse	PMID:12591952
Cellular Component	GO:0140225	DNA topoisomerase III-beta-TDRD3 complex	TOP3B	IPI		Human	PMID:28176834
Cellular Component	GO:0005634	nucleus	TOP3B	IDA		Human	PMID:23912945
Biological Process	GO:0007059	chromosome segregation	Top3b	IMP	MGI:MGI:2388157	Mouse	PMID:12591952

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern