Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TOMM40
  • Mouse genes Tomm40
  • Rat genes Tomm40
  • Zfish genes tomm40,tomm40l
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tomm40

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005261	monoatomic cation channel activity	Tomm40	IDA		Rat	PMID:15347672|RGD:8554396
Molecular Function	GO:0070678	preprotein binding	Tomm40	IDA		Rat	PMID:15347672|RGD:8554396
Molecular Function	GO:0005515	protein binding	TOMM40	IPI	UniProtKB:Q9BSF4	Human	PMID:27554484
Molecular Function	GO:0005515	protein binding	TOMM40	IPI	UniProtKB:P51572	Human	PMID:31206022
Molecular Function	GO:0005515	protein binding	TOMM40	IPI	UniProtKB:Q2TAZ0	Human	PMID:31412244
Molecular Function	GO:0005515	protein binding	Tomm40	IPI	UniProtKB:P00185	Rat	PMID:19401463|RGD:13838795
Molecular Function	GO:0008320	protein transmembrane transporter activity	Tomm40	IMP		Rat	PMID:18687331|RGD:8554729
Cellular Component	GO:0005829	cytosol	TOMM40	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016020	membrane	TOMM40	IDA		Human	PMID:15644312
Cellular Component	GO:0044233	mitochondria-associated endoplasmic reticulum membrane	TOMM40	IDA		Human	PMID:31206022
Cellular Component	GO:0005743	mitochondrial inner membrane	TOMM40	IDA		Human	PMID:24746669
Cellular Component	GO:0031966	mitochondrial membrane	Tomm40	IDA		Mouse	PMID:15136728
Cellular Component	GO:0005741	mitochondrial outer membrane	Tomm40	IDA		Mouse	PMID:28376086
Cellular Component	GO:0005741	mitochondrial outer membrane	Tomm40	IDA		Rat	PMID:10980201|RGD:1303948
Cellular Component	GO:0005742	mitochondrial outer membrane translocase complex	TOMM40	IDA		Human	PMID:12198123
Cellular Component	GO:0005742	mitochondrial outer membrane translocase complex	TOMM40	IDA		Human	PMID:15644312
Cellular Component	GO:0005742	mitochondrial outer membrane translocase complex	Tomm40	IDA		Rat	PMID:10980201|RGD:1303948
Cellular Component	GO:0005739	mitochondrion	TOMM40	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005739	mitochondrion	Tomm40	HDA		Mouse	PMID:14651853
Cellular Component	GO:0005739	mitochondrion	Tomm40	IDA		Mouse	PMID:12931191
Cellular Component	GO:0005739	mitochondrion	Tomm40	HDA		Mouse	PMID:18614015
Cellular Component	GO:0005739	mitochondrion	Tomm40	IDA		Rat	PMID:10980201|RGD:1303948
Biological Process	GO:0043065	positive regulation of apoptotic process	Tomm40	IMP		Rat	PMID:18687331|RGD:8554729
Biological Process	GO:0051204	protein insertion into mitochondrial membrane	Tomm40	IMP		Rat	PMID:18687331|RGD:8554729
Biological Process	GO:0006626	protein targeting to mitochondrion	TOMM40	IMP		Human	PMID:15644312
Biological Process	GO:0006626	protein targeting to mitochondrion	TOMM40	IGI	UniProtKB:P51572	Human	PMID:31206022
Biological Process	GO:0006626	protein targeting to mitochondrion	Tomm40	IDA		Rat	PMID:10980201|RGD:1303948
Biological Process	GO:0006626	protein targeting to mitochondrion	Tomm40	IMP		Rat	PMID:15347672|RGD:8554396
Biological Process	GO:0006626	protein targeting to mitochondrion	Tomm40	IMP		Rat	PMID:19401463|RGD:13838795

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern